Results 1 to 10 of about 182,958 (167)
Role of MMP-2 and CD147 in kidney fibrosis
Open Life Sciences, 2022 Matrix metalloproteinase-2 (MMP-2) and cluster of differentiation 147 (CD147) both play important roles in the development of kidney fibrosis, and CD147 can induce the production and activation of MMP-2.
Cheng Zhengyuan +4 more
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Mutiara Medika, 2021 Malignant peripheral nerve sheath tumor (MPNST) is a soft tissue sarcoma, which is difficult to distinguish from other spindle cell sarcomas. MPNST is hostile, with a high recurrence, and tends to metastasize hematogenously, especially to the lungs.
Niniek Hardini +2 more
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MMP-2 and MMP-9 gene polymorphisms and risk of head and neck carcinomas
Romanian Journal of Laboratory Medicine, 2022 Background: Head and neck carcinomas (HNC) account for a majority of ear, nose and throat tumours. They account for 6.3% of all incident malignancies and 6.2 % of all deaths from cancer in Romania in 2020, the fifth most common cancer in this Eastern ...
Schipor Sorina +4 more
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Role of Matrix Metalloproteinases and Their Inhibitors in Locally Invasive Papillary Thyroid Cancer
Biomedicines, 2022 Locally invasive papillary thyroid carcinoma (PTC) protrudes beyond the thyroid capsule and invades local structures. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are implicated in local invasion and metastasis in PTC.
Irena Ivković +4 more
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Türk Biyokimya Dergisi, 2022 Adipose tissue mediates various bioactive molecules and cytokine discharge. The anti-inflammatory cytokine, interleukin-10 (IL-10), has roles in systemic inflammation.
Aksoyer Sezgin Saadet Busra +6 more
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A drug cocktail for protecting against ischemia-reperfusion injury
Frontiers in Bioscience-Landmark, 2020 Ischemia followed by reperfusion (I/R) of cardiomyocytes causes release of a large amount of inducible nitric oxide (NO) synthase (iNOS) followed by an increase of asymmetric dimethylarginine (ADMA).
Anna Krzywonos-Zawadzka +3 more
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Российский кардиологический журнал, 2022 The article is devoted to the modern understanding of endothelial dysfunction development, the role of hyperhomocysteinemia, and, as a consequence, hypertension in patients with multiple myeloma receiving multiagent chemotherapy.
I. L. Davydkin +4 more
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Bone sialoprotein does not interact with pro-gelatinase A (MMP-2) or mediate MMP-2 activation [PDF]
BMC Cancer, 2009 Abstract Background A recent model for activation of the zymogen form of matrix metalloproteinase 2 (MMP-2, also known as gelatinase A) has suggested that interactions between the SIBLING protein bone sialoprotein (BSP) and MMP-2 leads to conformational change in MMP-2 that initiates the conversion of the pro-enzyme ...
Hwang, Queena +4 more
openaire +4 more sources
Monitoring MMP-2 and MMP-7 levels in traumatic wounds of the ocular adnexa
Journal of Ophthalmology, 2021 Background: Matrix metalloproteinase (MMP)-2 and MMP-9 are gelatinases involved in many physiological and pathological processes including inflammation and angiogenesis, which make up the basis for tissue remodeling and repair. Prolonged inflammation and
O. V. Petrenko +3 more
doaj +1 more source
MMP-2 and 9 in Chronic Kidney Disease [PDF]
International Journal of Molecular Sciences, 2017 Gelatinases are members of the matrix metalloproteinase (MMPs) family; they play an important role in the degradation of the extracellular matrix (ECM). This effect is also crucial in the development and progression of chronic kidney disease (CKD). Its expression, as well as its activity regulation are closely related to the cell signaling pathways ...
Cheng, Zhengyuan +7 more
openaire +2 more sources