Results 1 to 10 of about 24,793,258 (262)

Differences in MMP-2 Expression in High- and Low-Grade MPNST and its Correlation with Prognostic Factors

Mutiara Medika, 2021
Malignant peripheral nerve sheath tumor (MPNST) is a soft tissue sarcoma, which is difficult to distinguish from other spindle cell sarcomas. MPNST is hostile, with a high recurrence, and tends to metastasize hematogenously, especially to the lungs.
Niniek Hardini, Nurjati Chairani Siregar, Puspita Eka Wuyung   +2 more
doaj   +1 more source

MMP-2 and MMP-9 gene polymorphisms and risk of head and neck carcinomas

Romanian Journal of Laboratory Medicine, 2022
Background: Head and neck carcinomas (HNC) account for a majority of ear, nose and throat tumours. They account for 6.3% of all incident malignancies and 6.2 % of all deaths from cancer in Romania in 2020, the fifth most common cancer in this Eastern ...
Schipor Sorina, Zamfir Adina, Gheorghe Dan Cristian, Picu Catalina, Manda Dana   +4 more
doaj   +1 more source

Role of Matrix Metalloproteinases and Their Inhibitors in Locally Invasive Papillary Thyroid Cancer

Biomedicines, 2022
Locally invasive papillary thyroid carcinoma (PTC) protrudes beyond the thyroid capsule and invades local structures. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are implicated in local invasion and metastasis in PTC.
Irena Ivković, Zgjim Limani, Antonia Jakovčević, Dražen Huić, Drago Prgomet   +4 more
doaj   +1 more source

Role of MMP-2 and CD147 in kidney fibrosis

Open Life Sciences, 2022
Matrix metalloproteinase-2 (MMP-2) and cluster of differentiation 147 (CD147) both play important roles in the development of kidney fibrosis, and CD147 can induce the production and activation of MMP-2.
Cheng Zhengyuan, Zhang Xiaojuan, Zhang Yu, Li Li, Chen Pingsheng   +4 more
doaj   +1 more source

Downregulation of MMP-2 and MMP-9 genes in obesity patients and their relation with obesity-related phenotypes

Türk Biyokimya Dergisi, 2022
Adipose tissue mediates various bioactive molecules and cytokine discharge. The anti-inflammatory cytokine, interleukin-10 (IL-10), has roles in systemic inflammation.
Aksoyer Sezgin Saadet Busra, Bayoglu Burcu, Ersoz Feyzullah, Sarici Murat, Niyazoglu Mutlu, Dirican Ahmet, Cengiz Müjgan   +6 more
doaj   +1 more source

A drug cocktail for protecting against ischemia-reperfusion injury

Frontiers in Bioscience-Landmark, 2020
Ischemia followed by reperfusion (I/R) of cardiomyocytes causes release of a large amount of inducible nitric oxide (NO) synthase (iNOS) followed by an increase of asymmetric dimethylarginine (ADMA).
Anna Krzywonos-Zawadzka, Mieczyslaw Wozniak, Grzegorz Sawicki, Iwona Bil-Lula   +3 more
doaj   +1 more source

Changes in activity of metalloproteinases 2 and 9 in rat liver in experimental model of cholestasis taking into account its duration and assessment of selected features

Annales Academiae Medicae Silesiensis, 2023
INTRODUCTION: Cholestasis, otherwise known as bile stasis, occurs when the flow of bile is blocked. There are currently two types of cholestasis: extrahepatic and intrahepatic.
Krzysztof Suszyński, Natalia Białoń, Dariusz Górka, Anna Dolińska, Mikołaj Górka   +4 more
doaj   +1 more source

miR-338-3p inhibits cell growth, invasion, and EMT process in neuroblastoma through targeting MMP-2

Open Life Sciences, 2021
This study aimed to explore the regulatory mechanisms of miR-338-3p and matrix metalloproteinase-2 (MMP-2) in neuroblastoma. Putative target interaction regions of miR-338-3p on MMP-2 were predicted by miRcode and miRbase bioinformatics tools.
Yuan Haibin, Liu Fengli, Ma Tongsheng, Zeng Zhandong, Zhang Ning   +4 more
doaj   +1 more source

Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas

World Journal of Surgical Oncology, 2008
Background Extranodal T/NK cell lymphomas possess distinctive clinico-pathological characteristics: they are angiocentric, exhibit extensive necrosis. Prognosis is poor in the short term.
Roa Lourdes, Montes Adriana, Abarca Jorge, Betancourt Alejandro, Meneses-García Abelardo, Ruíz-Godoy Luz   +5 more
doaj   +1 more source

Role of homocysteine metabolism in the development of endothelial dysfunction and hypertension in patients with multiple myeloma

Российский кардиологический журнал, 2022
The article is devoted to the modern understanding of endothelial dysfunction development, the role of hyperhomocysteinemia, and, as a consequence, hypertension in patients with multiple myeloma receiving multiagent chemotherapy.
I. L. Davydkin, E. V. Mordvinova, T. P. Kuzmina, K. V. Naumova, E. S. Fatenkova   +4 more
doaj   +1 more source