Results 71 to 80 of about 121,710 (296)

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

The effect of a bilateral stellate ganglion block guided by ultrasound on postoperative cognitive function in elderly spinal patients

Central Asian Journal of Medical Sciences
Objective: Post-operative cognitive dysfunction (POCD) is a prevalent consequence of general anesthesia in older individuals (≥60 years) undergoing spine surgery.
Ya Tuo, Yi Qiu, Yulin Wu, Xueqiang Fu, Gundeg Ganbold   +4 more
doaj   +1 more source

Impact of Diabetes on Cognitive Functions: A Comparative Study of Diabetic and Non-Diabetic Individuals in Dakhla [PDF]

BIO Web of Conferences
Diabetes belongs to the chronic disease and is a progressive in nature causing an impact on many body organs including brain functions; such as cognition.
Aithammou Rachid, Louragli Ismail, Ben El Caid Mohamed   +2 more
doaj   +1 more source

Coordinated analysis of age, sex, and education effects on change in MMSE scores [PDF]

, 2013
We describe and compare the expected performance trajectories of older adults on the Mini-Mental Status Examination (MMSE) across six independent studies from four countries in the context of a collaborative network of longitudinal studies of aging.
Clouston, S., Thorvaldsson, V., Skoog, I., Johansson, B., Deary, Ian J., Deeg, Dorly J. H., Johansson, Boo, Mackinnon, Andrew, Deary, I. J., Starr, John M., Thorvaldsson, Valgeir, Skoog, Ingmar, Muniz-Terrera, G., Spiro, A., Thorvaldsson, Valgeir,, Muniz-Terrera, Graciela, Starr, J.J., Deeg, D., Johansson, Boo,, Spiro, Avron, Deary, I., Skoog, Ingmar,, Reynolds, C.A., Starr, J. M., Clouston, Sean, Piccinin, Andrea M., Deeg, D.J.H., Piccinin, A. M., Piccinin, A.M., Hofer, S.M., MacKinnon, A., Hofer, S. M., Reynolds, C. A., Reynolds, Chandra A., Hofer, Scott M.   +34 more
core   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Effect of subclinical esketamine on NLRP3 and cognitive dysfunction in elderly ischemic stroke patients

Open Medicine
This study investigates the effects of subclinical doses of esketamine on serum NLRP3 levels and early cognitive dysfunction in elderly ischemic stroke patients after neurointerventional procedures under general anesthesia.
Wang Lang, Ma Baoxin, Zhang Jianping
doaj   +1 more source

Is the MMSE enough for MCI? A narrative review of the usefulness of the MMSE

Frontiers in Psychology
Background Mild Cognitive Impairment (MCI) is a clinical condition characterized by a decline in cognitive functions greater than expected for an individual’s age and educational level, yet not severe enough to significantly interfere with daily activities.
D'Ignazio, Giorgia, Carlucci, Leonardo, Sergi, Maria Rita, Palumbo, Rocco, Dattilo, Laura, Terrei, Michela, Balsamo, Michela   +6 more
openaire   +3 more sources

Risk-Aware MMSE Estimation

CoRR, 2019
18 pages, 4 ...
Dionysios S. Kalogerias, Luiz F. O. Chamon, George J. Pappas, Alejandro Ribeiro   +3 more
openaire   +3 more sources

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

Prevalence of neurocognitive impairments in adults with chronic pain: A cross-sectional study

South African Journal of Psychiatry
Background: There is a strong link between chronic pain and neurocognitive impairment. The co-occurrence of the two disorders often leads to a poor quality of life and significant disability. Aim: To determine the prevalence of neurocognitive impairments
Bonginkosi M.J Mafuze, Lindokuhle T. Thela   +1 more
doaj   +1 more source