Results 91 to 100 of about 38,824 (244)

Presence of a mouse mammary tumour virus-like in feline lymphomas: a preliminary study

Infectious Agents and Cancer, 2022
The mouse mammary tumour virus (MMTV) is implicated in the aetiology of murine mammary carcinomas and a variant of it, the type B leukemogenic virus, can cause murine thymic lymphomas. Interestingly, a MMTV-like virus is suspected to be involved in human
Francesca Parisi, Francesca Lessi, Michele Menicagli, Prospero Civita, Romano Liotti, Francesca Millanta, Giulia Freer, Mauro Pistello, Chiara Maria Mazzanti, Alessandro Poli   +9 more
doaj   +1 more source

Exploring the Key Role of Nanotechnology on Intratumoral Microbiome Modulation for Cancer Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
wiley   +1 more source

The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains [PDF]

, 2011
The ATP-dependent chromatin-remodelling enzyme Chd1 is a 168-kDa protein consisting of a double chromodomain, Snf2-related ATPase domain, and a C-terminal DNA-binding domain.
Aasland, Adams, Alen, Awad, Bailey, Baker, Baudin, Bird, Biswas, Biswas, Blank, Blosser, Boyer, Cairns, Chen, Cheng, Clapier, Clapier, Corona, Dang, Daniel P Ryan, Daubresse, David Martin, de Vries, Delmas, Eberharter, Eddy, Emsley, Fazzio, Ferreira, Flanagan, Flaus, Gangaraju, Gaspar-Maia, Grune, Hamiche, Hauk, Holm, Konev, Kouzarides, Lin, Lusser, McDaniel, Morettini, Okuda, Painter, Park, Pinskaya, Racki, Ramasubramanian Sundaramoorthy, Robinson, Sikorski, Simic, Sims, Stockdale, Stokes, Thastrom, Thompson, Tom Owen-Hughes, Tran, Tsukiyama, Vijender Singh, Walfridsson, Waterhouse, Yang, Zentner   +65 more
core   +4 more sources

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, Volume 13, Issue 8, 9 February 2026.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Detection of MMTV-Like sequences in Moroccan breast cancer cases

Infectious Agents and Cancer, 2014
IntroductionThe mouse mammary tumor virus (MMTV) like sequences have been reported to be present in some human breast cancers, but their association with breast cancer development is still controversial.MethodsIn this retrospective study, we investigated
M. Slaoui, M. El Mzibri, R. Razine, Zineb Qmichou, Mohammed Attaleb, M. Amrani   +5 more
semanticscholar   +1 more source

Topical Formulations Containing Mentha piperita for Wound Healing: A Scoping Review

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
This scoping review synthesizes evidence from preclinical studies on topical formulations containing Mentha piperita for the treatment of infected wounds. The formulations, including creams, hydrogels, nanoemulsions, and lipid carriers, demonstrated antimicrobial and healing potential, reducing bacterial growth, biofilm formation, and inflammation, in ...
Lorena Gonçalves Araújo, Beatriz Gomes Vila‐Nova, Afonso Gomes Abreu   +2 more
wiley   +1 more source

Immunosurveillance and immunoediting in MMTV-PyMT-induced mammary oncogenesis [PDF]

OncoImmunology, 2017
Evidence of cancer immunosurveillance and immunoediting processes has been primarily demonstrated in mouse models of chemically induced oncogenesis. Although these models are very tractable, they are characterized by high mutational loads that represent a minority of human cancers. In this study, we sought to determine whether cancer immunosurveillance
Gross, Emilie TE, Han, Semi, Vemu, Prasantha, Peinado, Carlos D, Marsala, Martin, Ellies, Lesley G, Bui, Jack D   +6 more
openaire   +5 more sources

Detection of Mouse Mammary Tumor Virus-Like Sequence (MMTVLike Sequence) in the Breast Cancer of Iraqi Women Samples by Nested PCR.

Kufa Journal for Nursing Sciences, 2014
Background: Since the discovery of MMTV in the high cancer strains of mice capable of initiating mammary tumors, and its subsequent identification as a B-type RNA virus, several evidence has been accumulated supporting the attractive hypothesis that a ...
Asaad Al-janabi, Ahmed Mohammed Ali Nazar, Hashim Raheem Tarish   +2 more
doaj   +1 more source

RCC1 Domain‐Containing Protein 1 Promotes Colon Cancer Malignant Progression by Activating Autophagy‐Dependent WNT5A Secretion in Cancer‐Associated Fibroblasts

Journal of the Royal Society of New Zealand, Volume 56, Issue 1, February 2026.
RCCD1 is upregulated in colon cancer and cancer‐associated fibroblasts (CAFs). In CAFs, RCCD1 overexpression activates AMPK/mTOR/ULK1 signaling, enhancing autophagy. This stimulates autophagic secretion of WNT5A. WNT5A then activates the nonclassical Wnt/CaMKII/ERK pathway in tumor cells, promoting epithelial‐mesenchymal transition (EMT), proliferation,
Chao Liu, Sheng Xu, Yuanyuan Liu, Yuntian Tang   +3 more
wiley   +1 more source

ORGAN SPECIFIC VASCULAR RESPONSE TO FIBROSIS AFFECTS BREAST CANCER METASTATIC ORGANOTROPISM [PDF]

, 2016
The solid tumor microenvironment, pre-metastatic niche, and fibrotic environment are known to have significant biochemical and biomechanical similarities to the fibrotic environment. All have significantly increased levels of factors such as TGFβ, HIF1α,
Fletcher, Eliot S, Fletcher, Eliot S
core   +1 more source