Results 111 to 120 of about 38,824 (244)
Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression [PDF]
Breast Cancer Research, 2009 Abstract Introduction Rho signaling regulates key cellular processes including proliferation, survival, and migration, and it has been implicated in the development of many types of cancer including breast cancer.
Heckman-Stoddard, Brandy M +7 more
openaire +3 more sources
Flavour violating squark and gluino decays at LHC
, 2012 We study the effects of squark generation mixing on squark and gluino production and decays at LHC in the Minimal Supersymmetric Standard Model (MSSM) with focus on the mixing between second and third generation squarks.
Bartl, A. +6 more
core +2 more sources
Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. [PDF]
, 2018 Both adjuvants and focal ablation can alter the local innate immune system and trigger a highly effective systemic response. Our goal is to determine the impact of these treatments on directly treated and distant disease and the mechanisms for the ...
Borowsky, Alexander D +13 more
core +1 more source
PLoS ONE, 2013 Cancer metastases arise in part from disseminated tumor cells originating from the primary tumor and from residual disease persisting after therapy. The identification of biomarkers on micro-metastases, disseminated tumors, and residual disease may yield
C. Franci +6 more
semanticscholar +1 more source
Cancer Medicine, Volume 15, Issue 1, January 2026.ABSTRACT Background Adiposity‐Based Chronic Disease (ABCD), a novel model housing obesity, insulin resistance, and adipokine‐related inflammation, increases the risk of aggressive prostate cancer (PCa), posttreatment PCa recurrence, and PCa mortality. This paper provides a new network analysis of relevant metabolic drivers to provide insight into the ...
Zachary Dovey +2 more
wiley +1 more source
Neoplasia, 2008 Distant metastases of human breast cancers have been suggested to be more different from each other than from their respective primary tumors, based on expression profiling. The mechanism behind this lack of similarity between individual metastases is not known.
Shixia Huang +3 more
openaire +3 more sources
Wnt5a Signaling in Normal and Cancer Stem Cells. [PDF]
, 2017 Wnt5a is involved in activating several noncanonical Wnt signaling pathways, which can inhibit or activate canonical Wnt/β-catenin signaling pathway in a receptor context-dependent manner.
Kipps, Thomas J +2 more
core +2 more sources
MedComm, Volume 7, Issue 1, January 2026.The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li +5 more
wiley +1 more source
Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo [PDF]
, 2012 INTRODUCTION: Activation of focal adhesion kinase (FAK) is hypothesized to play an important role in the pathogenesis of human breast cancer. METHODS: To directly evaluate the role of FAK in mammary tumour progression, we have used a conditional FAK ...
AL Lark +35 more
core +1 more source
Breast Cancer Research, 2013 IntroductionDespite continued improvements in diagnosis, surgical techniques, and chemotherapy, breast cancer patients are still overcome by cancer metastasis.
M. Hallett +5 more
semanticscholar +1 more source