Results 31 to 40 of about 38,824 (244)

Restriction of MMTV by APOBEC3 [PDF]

Retrovirology, 2011
Background Host cells have developed a broad range of mechanisms to counteract retroviral infection. Besides Trim5a (tripartite motif-containing protein 5alpha) and Tetherin, APOBEC3 proteins (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3), especially APOBEC3G and APOBEC3F, are major factors in the post entry inhibition of ...
Kraase Martin, Konstantoulas Constantine, Indik Stanislav   +2 more
openaire   +2 more sources

WNT10B (wingless-type MMTV integration site family) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2018
WNT10B is a member of the WNT ligand gene family encoding a secreted growth factor that has been reported to have role in a wide range of biological actions. Wnt10b was originally identified from mouse embryos and the virgin mammary gland, the locus was cloned by retroviral insertional activation, similar to the strategy used to identify other mammary ...
A. Beghini, F. Lazzaroni
openaire   +2 more sources

Association of Mouse Mammary Tumor Virus With Human Breast Cancer: Histology, Immunohistochemistry and Polymerase Chain Reaction Analyses

Frontiers in Oncology, 2018
PurposeThe purpose of this study is to determine whether mouse mammary tumor virus (MMTV)-associated human breast cancer has the same or similar histology to MMTV-associated mouse mammary tumors.
James S. Lawson, Chiara Mazzanti, Prospero Civita, Michele Menicagli, Christopher C. Ngan, Noel J. Whitaker, Jacob Hochman, Ori Braitbard, Benafsha Yosufi, Wendy K. Glenn   +9 more
doaj   +1 more source

Intestinal Immune System and Amplification of Mouse Mammary Tumor Virus

Frontiers in Cellular and Infection Microbiology, 2022
Mouse mammary tumor virus (MMTV) is a virus that induces breast cancer in mice. During lactation, MMTV can transmit from mother to offspring through milk, and Peyer’s patches (PPs) in mouse intestine are the first and specific target organ.
Lankai Chen, Xipeng Zhang, Guisheng Liu, Shuo Chen, Minying Zheng, Siwei Zhu, Shiwu Zhang   +6 more
doaj   +1 more source

Investigation of human papillomaviruses (HPV), mouse mammary tumour virus (MMTV), Epstein–Barr virus (EBV), and human polyomavirus entities in canine mammary tumours

Journal of Veterinary Research, 2016
Introduction: The aim of the study was to investigate the presence of human papillomaviruses (HPV), mouse mammary tumour virus (MMTV), Epstein-Barr virus (EBV), and human polyomavirus BK in canine mammary tumours (CMTs) and to correlate the results of ...
Sonmez Kivilcim, Altan Eda, Yildirim Funda, Arun Seçkin Serdar, Turan Nuri, Yilmaz Huseyin, Kuskucu Mert Ahmet   +6 more
doaj   +1 more source

Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease [PDF]

, 2014
R-Ras2 is a transforming GTPase that shares downstream effectors with Ras subfamily proteins. However, little information exists about the function of this protein in tumorigenesis and its signalling overlap with classical Ras GTPases.
Alarcón, Balbino, Bustelo, Xosé R., Cañamero, Marta, de Alava, Enrique, Dosil, Mercedes, Larive, Ramon, Menacho Márquez, Mauricio Ariel, Moriggi, Giulia   +7 more
core   +3 more sources

Oncogenic Viruses and Breast Cancer: Mouse Mammary Tumor Virus (MMTV), Bovine Leukemia Virus (BLV), Human Papilloma Virus (HPV), and Epstein–Barr Virus (EBV)

Frontiers in Oncology, 2018
Background Although the risk factors for breast cancer are well established, namely female gender, early menarche and late menopause plus the protective influence of early pregnancy, the underlying causes of breast cancer remain unknown.
J. Lawson, Brian Salmons, W. Glenn
semanticscholar   +1 more source

Tissue Distribution of Mouse Mammary Tumor Virus (MMTV) Antigens and Endogenous MMTV Loci in Japanese Laboratory Mouse Strains [PDF]

Japanese Journal of Cancer Research, 1991
The distribution of mouse mammary tumor virus (MMTV) antigens was studied by the immunoper‐oxidase method in the II‐TES and I‐TES mouse strains as well as their progenitors, CS and DBA/2 strains. In the II‐TES, I‐TES and CS strains, and BALB/c mice foster‐nursed with these strains, MMTV antigens were found not only in epithelial cells of the mammary ...
Wajjwalku, Worawidh, Takahashi, Masahide, Miyaishi, Osamu, Lu, Jin, Sakata, Keita, Yokoi, Toyoharu, Saga, Shinsuke, Imai, Masao, Matsuyama, Mutsushi, Hoshino, Munemitsu   +9 more
openaire   +2 more sources

A Protein Antagonist of Activation-Induced Cytidine Deaminase Encoded by a Complex Mouse Retrovirus

mBio, 2019
Complex human-pathogenic retroviruses cause high morbidity and mortality worldwide, but resist antiviral drugs and vaccine development due to evasion of the immune response.
Gurvani B. Singh, Hyewon Byun, Almas F. Ali, Frank Medina, Dennis Wylie, Haridha Shivram, Andrea K. Nash, Mary M. Lozano, Jaquelin P. Dudley   +8 more
doaj   +1 more source

MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors. [PDF]

PLoS ONE, 2009
Canonical Wnt/beta-catenin signaling regulates stem/progenitor cells and, when perturbed, induces many human cancers. A significant proportion of human breast cancer is associated with loss of secreted Wnt antagonists and mice expressing MMTV-Wnt1 and ...
Brigitte Teissedre, Alicia Pinderhughes, Angela Incassati, Sarah J Hatsell, Minoti Hiremath, Pamela Cowin   +5 more
doaj   +1 more source