Results 41 to 50 of about 38,824 (244)

Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function [PDF]

, 2002
This work was supported by grants from the NIH (R01CA86072 to R.G.P. and R01CA72038-01 to S.A.W.F.) and The Susan Komen Breast Cancer Foundation (to R.G.P.). R.T.H. and E.J. were supported by the Medical Research Council. Y.-G.Y.
Chang, Chawnshang, Fu, Maofu, Fuqua, Suzanne A W, Hay, Ronald Thomas, Hopp, Torsten, Jaffray, E, Janne, OA, Palvimo, Jorma J, Pestell, RG0, Sakamaki, Toshiyuki, Wang, Chenguang, Wang, Jian, Yeung, YG, Zhang, Xueping   +13 more
core   +1 more source

Prevalence of MMTV-Like env Sequences and Its Association with BRCA1/2 Genes Mutations Among Egyptian Breast Cancer Patients

Cancer Management and Research, 2021
Samah A Loutfy,1 Zeinab F Abdallah,1 Mohamed Shaalan,2 Mohamed Moneer,3 Adel Karam,3 Manar M Moneer,4 Ibrahim M Sayed,5,6 Amer Ali Abd El-Hafeez,7,8 Pradipta Ghosh,8– 10 Abdel-Rahman N Zekri1 1Virology and Immunology Unit, Cancer Biology Department,
Loutfy SA, Abdallah ZF, Shaalan M, Moneer M, Karam A, Moneer MM, Sayed IM, Abd El-Hafeez AA, Ghosh P, Zekri ARN   +9 more
doaj  

Mouse mammary tumour virus (MMTV) and human breast cancer with neuroendocrine differentiation

Infectious Agents and Cancer, 2017
Background Mouse mammary tumour viruses (MMTVs) may have a role in a subset of human breast cancers. MMTV positive human breast cancers have similar histological characteristics to neuroendocrine breast cancers and to MMTV positive mouse mammary tumours.
Lawson JS, Ngan CC, Glenn WK, Tran DD
doaj   +1 more source

Prevalence and characteristics of mouse mammary tumor virus-like virus associated breast cancer in China

Infectious Agents and Cancer, 2021
Background Despite extensive molecular epidemiological studies, the prevalence and characteristics of Mouse Mammary Tumor Virus-Like Virus (MMTV-LV) in Chinese women breast cancer are still unclear.
Fa-liang Wang, Xiao-li Zhang, Ming Yang, Jun Lin, Yong-fang Yue, Ya-dan Li, Xian Wang, Qiang Shu, Hong-chuan Jin   +8 more
doaj   +1 more source

Development of Hyperplasias, Preneoplasias, and Mammary Tumors in MMTV-c-erbB-2 and MMTV-TGFα Transgenic Rats [PDF]

The American Journal of Pathology, 1999
Human cDNAs corresponding to two epidermal growth factor-related products that are overexpressed in human breast cancers, that for c-erbB-2 (HER-2) and for transforming growth factor alpha (TGFalpha), have been cloned downstream of the mouse mammary tumor virus (MMTV) long terminal repeat promoter and injected into the pronucleus of fertilized oocytes ...
B R, Davies, A M, Platt-Higgins, G, Schmidt, P S, Rudland   +3 more
openaire   +3 more sources

Mouse mammary tumor virus (MMTV) - like exogenous sequences are associated with sporadic but not hereditary human breast carcinoma

Aging, 2019
The inheritance of mutated suppressor genes, such as BRCA1 and BRCA2, is acknowledged as an etiological factor in hereditary breast carcinoma (HBC). Two different molecular mechanisms are possible; the Knudson’s “two hits” or the gene haploinsufficiency.
A. Naccarato, F. Lessi, K. Zavaglia, C. Scatena, Mohammad Al Hamad, P. Aretini, M. Menicagli, M. Roncella, M. Ghilli, M. Caligo, C. Mazzanti, G. Bevilacqua   +11 more
semanticscholar   +1 more source

ATP-dependent chromatosome remodeling [PDF]

, 2008
Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime.
Dimitrov S., Langst G., Loyola A., Ner S.S., Shogren-Knaak M., Varga-Weisz P.D., Wisniewski J.R.   +6 more
core   +1 more source

Mouse mammary tumour virus-like env nucleotide and p14 signal peptide are present in feline mammary carcinomas, but not in neoplastic or dysplastic canine mammary lesions. [PDF]

PLoS ONE, 2018
Mouse mammary tumour virus-like (MMTV-like) is suspected to be involved in human breast cancer and it has been hypothesized that companion animals might have a role in viral transmission.
Prospero Civita, Michele Menicagli, Claudia Scopelliti, Francesca Lessi, Francesca Millanta, Sara Borsacchi, Francesca Parisi, Giulia Freer, Mauro Pistello, Chiara Maria Mazzanti, Alessandro Poli   +10 more
doaj   +1 more source

Global Down-regulation of Gene Expression Induced by Mouse Mammary Tumor Virus (MMTV) in Normal Mammary Epithelial Cells

Viruses, 2023
Mouse mammary tumor virus (MMTV) is a betaretrovirus that causes breast cancer in mice. The mouse mammary epithelial cells are the most permissive cells for MMTV, expressing the highest levels of virus upon infection and being the ones later transformed ...
Waqar Ahmad, Neena G. Panicker, Shaima Akhlaq, Bushra Gull, Jasmin Baby, Thanumol A. Khader, Tahir A. Rizvi, Farah Mustafa   +7 more
doaj   +1 more source

Mouse mammary tumor-like virus (MMTV) is present in human breast tissue before development of virally associated breast cancer

Infectious Agents and Cancer, 2017
BackgroundThere is substantial evidence that a virus homologous to mouse mammary tumor virus (MMTV) may have a role in human breast cancer. The present study indicates that those who developed breast cancer associated with an MMTV-like virus had this ...
Teiko Nartey, C. Mazzanti, S. Melana, W. Glenn, G. Bevilacqua, J. Holland, N. Whitaker, J. Lawson, B. Pogo   +8 more
semanticscholar   +1 more source