Results 81 to 90 of about 200,952 (195)

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Flavonoid Profile, Biological Potentials, and In Silico Approaches of Methanol Extracts on AChE: Amaranthus retroflexus L.

Chemistry &Biodiversity, EarlyView.
ABSTRACT This study investigated the flavonoid compounds and their biological activities in methanol extracts obtained from root, stem, leaf, and flower parts of Amaranthus retroflexus L. Flavonoids in the extracts were characterized for the first time by liquid chromatography–highresolution mass spectrometry (LC–HRMS), and a total of eight flavonoid ...
Bedrettin Selvi, Güler Durmuş, Mustafa Ceylan, Şuheda Yıldırım, Ümit M. Koçyiğit, Ümit Yırtıcı, Volkan Eyüpoğlu   +6 more
wiley   +1 more source

Label‐Free Photonic Biosensors: Key Technologies for Precision Diagnostics

ChemistryEurope, EarlyView.
Photonic biosensors are versatile technologies promising unique advantages to improve current diagnosis workflows. On‐going research is directed to systems integration and automation as well as enhancing assay performance. Advances in bioengineering, material sciences, and photonics engineering will be the key toward their eventual implementation as ...
Maria Soler, Laura M. Lechuga
wiley   +1 more source

Study on the effect of co‐plasticization of post‐industrial starch for high‐impact thermoplastic starch development

The Canadian Journal of Chemical Engineering, EarlyView.
High‐impact thermoplastic starch blends through the co‐plasticization methodology. Abstract This study analyzed the effect of employing plasticized or co‐plasticized post‐industrial starch in developing PBAT‐based thermoplastic starch (TPS) blends. In this work, the post‐industrial wheat starch was co‐plasticized with glycerol‐urea, glycerol‐citric ...
Aarsha Surendren, Amar K. Mohanty, Loong‐Tak Lim, Qiang Liu, Bassim Abbassi, Manjusri Misra   +5 more
wiley   +1 more source

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

Cytoskeleton, EarlyView.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro, Shashank Shekhar, Stefanie M. Novak, Sudipta Biswas, Carol C. Gregorio, Velia M. Fowler   +5 more
wiley   +1 more source

Directory-based incentive management services for ad-hoc mobile clouds

Mobile cloud computing is envisioned as a promising approach to augment the computational capabilities of mobile devices for emerging resource-intensive mobile applications.
Chang, Victor, Gani, Abdullah, Noor, Rafidah Md, Yousafzai, Abdullah   +3 more
core   +1 more source

Novel 4,5‐Dihydrothiazole‐phenylpiperazine Derivatives: Synthesis, Docking Studies and Pharmacological Evaluation as Serotonergic Agents

ChemMedChem, Accepted Article.
We have described the synthesis of a new series of LCAPs (long‐chain arylpiperazine) as serotoninergic ligands (FG 1‐18). The combination of structural elements including heterocyclic nucleus, propyl chain and 4,5‐dihydrothiazol‐2‐ylphenylpiperazines, led to the preparation of different derivatives tested for their affinity toward 5‐HT1A, 5‐HT2A and 5 ...
Giorgia Andreozzi, Natalia Karkoszka, Rosa Sparaco, Angela Corvino, Beatrice Severino, Vincenzo Santagada, Elisa Magli, Ewa Gibuła-Tarłowska, Jolanta H. Kotlińska, Kinga Gawel, Raffaele Capasso, Anna Lesniak, Nataliia Semenko, Agnieszka A. Kaczor, Anna Bielenica, Grażyna Biała, Giuseppe Caliendo, Ewa Kędzierska, Ferdinando Fiorino   +18 more
wiley   +1 more source

The Interplay of Public Administration and Community Resilience During the COVID‐19 Pandemic—A Rapid Scoping Review

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This rapid scoping review examines the interplay between public administration and community resilience during the COVID‐19 pandemic, focusing on the type of research conducted, emerging themes in resilience studies, and key lessons learned. The findings show that research in the Global North has primarily examined resilience at the city level,
Daniela Gröschke
wiley   +1 more source

Spontaneous Contact and Social Resilience Following Eruption of Interethnic Violence in Ethnically Mixed Settings

Conflict Resolution Quarterly, EarlyView.
ABSTRACT Does spontaneous contact between individuals from different ethnonational groups affect their social resilience, specifically their ability to avoid escalation and radicalization following eruptions of ethnic violence? To address this question, we conducted a series of studies in mixed Jewish–Palestinian cities and academic settings.
Nitzan Faibish, Ifat Maoz, Paz Yaacov, Dan Miodownik   +3 more
wiley   +1 more source

Contribution of non‐orthogonal multiple access signalling to practical multibeam satellite deployments

International Journal of Satellite Communications and Networking, EarlyView., 2023
The potential gains of NOMA were evaluated in a satellite system with heterogeneous receivers, after considering the use of specific DVB‐S2X MODCODs, along with the impact of non‐linearities. It was concluded that a judicious power allocation in NOMA, jointly optimized with the IBO of the PAs, can yield significant sum‐rate gains.
Tomás Ramírez, Carlos Mosquera
wiley   +1 more source