Results 61 to 70 of about 389,080 (344)

Meeting report: mobile genetic elements and genome plasticity 2018

Mobile DNA, 2018
The Mobile Genetic Elements and Genome Plasticity conference was hosted by Keystone Symposia in Santa Fe, NM USA, February 11–15, 2018. The organizers were Marlene Belfort, Evan Eichler, Henry Levin and Lynne Maquat.
John M. Abrams, Irina R. Arkhipova, Marlene Belfort, Jef D. Boeke, M. Joan Curcio, Geoffrey J. Faulkner, John L. Goodier, Ruth Lehmann, Henry L. Levin   +8 more
doaj   +1 more source

Identifying Structural Variation in Haploid Microbial Genomes from Short-Read Resequencing Data Using Breseq [PDF]

, 2014
Mutations that alter chromosomal structure play critical roles in evolution and disease, including in the origin of new lifestyles and pathogenic traits in microbes.
Barrick, Jeffrey E., Borges, Jordan J., Colburn, Geoffrey, Deatherage, Daniel E., Knoester, David B., Meyer, Austin G., Reba, Aaron, Strand, Matthew D., Traverse, Charles C.   +8 more
core   +1 more source

Shuffling of mobile genetic elements (MGEs) in successful healthcare-associated MRSA (HA-MRSA). [PDF]

, 2012
Methicillin-resistant Staphylococcus aureus (MRSA) CC22 SCCmecIV is a successful hospital-associated (HA-) MRSA, widespread throughout the world, and now the dominant clone in UK hospitals.
Budd, EL, Knight, GM, Lindsay, JA, McCarthy, AJ   +3 more
core   +1 more source

Interplay between the cell envelope and mobile genetic elements shapes gene flow in populations of the nosocomial pathogen Klebsiella pneumoniae

PLoS Biology, 2021
Mobile genetic elements (MGEs) drive genetic transfers between bacteria using mechanisms that require a physical interaction with the cellular envelope.
Matthieu Haudiquet, A. Buffet, Olaya Rendueles, E. Rocha   +3 more
semanticscholar   +1 more source

Anti-phage islands force their target phage to directly mediate island excision and spread. [PDF]

, 2018
Vibrio cholerae, the causative agent of the diarrheal disease cholera, is antagonized by the lytic phage ICP1 in the aquatic environment and in human hosts. Mobile genetic elements called PLEs (phage-inducible chromosomal island-like elements) protect V.
McKitterick, Amelia C, Seed, Kimberley D
core   +1 more source

The Hypercomplex Genome of an Insect Reproductive Parasite Highlights the Importance of Lateral Gene Transfer in Symbiont Biology

mBio, 2020
Mobile elements—plasmids and phages—are important components of microbial function and evolution via traits that they encode and their capacity to shuttle genetic material between species. We here report the unusually rich array of mobile elements within
Crystal L. Frost, Stefanos Siozios, Pol Nadal-Jimenez, Michael A. Brockhurst, Kayla C. King, Alistair C. Darby, Gregory D. D. Hurst   +6 more
doaj   +1 more source

Making serine integrases work for us [PDF]

, 2017
DNA site-specific recombinases are enzymes (often associated with mobile DNA elements) that catalyse breaking and rejoining of DNA strands at specific points, thereby bringing about precise genetic rearrangements.
Stark, W. Marshall
core   +1 more source

Spatial mapping of mobile genetic elements and their bacterial hosts in complex microbiomes

Nature Microbiology
The exchange of mobile genetic elements (MGEs) facilitates the spread of functional traits including antimicrobial resistance within bacterial communities.
Benjamin Grodner, Hao Shi, Owen Farchione, A. C. Vill, Ioannis Ntekas, Peter Diebold, David T Wu, Chia-Yu Chen, David M. Kim, Warren R Zipfel, I. Brito, Iwijn De Vlaminck   +11 more
semanticscholar   +1 more source

Rapid evolutionary turnover of mobile genetic elements drives bacterial resistance to phages

Science, 2021
Description Wild phage evolution Bacteria possess a diversity of highly specific phage defense mechanisms that evolve rapidly and that account for a large proportion of bacterial genomes.
F. Hussain, Javier Dubert, Joseph Elsherbini, Mikayla Murphy, David VanInsberghe, P. Arevalo, Kathryn M. Kauffman, B. Rodiño-Janeiro, Hannah E. Gavin, Annika L. Gomez, A. Lopatina, F. Le Roux, M. Polz   +12 more
semanticscholar   +1 more source

Metagenomic assembly is the main bottleneck in the identification of mobile genetic elements

PeerJ
Antimicrobial resistance genes (ARG) are commonly found on acquired mobile genetic elements (MGEs) such as plasmids or transposons. Understanding the spread of resistance genes associated with mobile elements (mARGs) across different hosts and ...
Jesse J. Kerkvliet, Alex Bossers, J. G. Kers, Rodrigo Meneses, R. Willems, A. Schürch   +5 more
semanticscholar   +1 more source