Results 91 to 100 of about 3,141,117 (304)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Association of Specific Leg Muscle Strength and Motor Features in Parkinson’s Disease
Parkinson's DiseaseBackground. Postural instability and gait difficulties (PIGD) are a significant cause of falls, mobility loss, and lower quality of life in Parkinson’s disease (PD).
Chatkaew Pongmala +6 more
doaj +1 more source
Hot axle box detectors hot wheel detectors: towards a harmonised, digital and international safety framework [PDF]
Railway SciencesPurposeThis paper presents an integrated technical and economic assessment of hot axle box detectors (HABD) and hot wheel detectors (HWD) important components of derailment prevention strategies, whose role extends beyond auxiliary monitoring to become ...
Joaquin Botella, José-Manuel Cabral
doaj +1 more source
Class Origins, Education and Occupational Attainment: Cross-cohort Changes among Men in Britain [PDF]
, 2009 Studies of intergenerational class mobility and of intragenerational occupational mobility have of late tended to diverge in their concerns and methodology.
Bukodi, Erzsebet, Goldthorpe, John H
core +1 more source
Modeling Endogenous Mobility in Wage Determination [PDF]
, 2015 We evaluate the bias from endogenous job mobility in fixed-effects estimates of worker- and firm-specific earnings heterogeneity using longitudinally linked employer-employee data from the LEHD infrastructure file system of the U.S. Census Bureau. First,
Abowd, John M +2 more
core +3 more sources
Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
IET Intelligent Transport Systems, 2020 Decision making for self‐driving cars is usually tackled by manually encoding rules from drivers’ behaviours or imitating drivers’ manipulation using supervised learning techniques.
Jingliang Duan +4 more
doaj +1 more source
, 2018 Transport of an inertial particle advected by a two-dimensional steady laminar flow is numerically investigated in the presences of a constant force and a periodic potential.
Ai, Bao-quan +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source