Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins +3 more
wiley +1 more source
When poverty gets into your joints: exploring socioeconomic, environmental, and gendered determinants of rheumatoid arthritis in district Dir lower, Pakistan. [PDF]
Khan Y +4 more
europepmc +1 more source
Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han +5 more
wiley +1 more source
Distance-decay reveals contrasting effects of land-use types on arthropod community homogenisation. [PDF]
Decker O +15 more
europepmc +1 more source
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He +4 more
wiley +1 more source
Analyzing Mega-mobility Systems in Smart Cities: A Macro-Micro Integration with Feedback Paradigm Empowered by Artificial Intelligence. [PDF]
Wang Z +10 more
europepmc +1 more source
An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou +11 more
wiley +1 more source
Leveraging the numerous advantages of ammonium‐ion (NH₄⁺)—including cost‐effectiveness, low corrosiveness, preferential orientation, and rapid diffusion kinetics—aqueous NH₄⁺ batteries (AAIBs) have gained significant attention. This review highlights and evaluates the progress of AAIBs utilizing organic electrode materials such as small molecules ...
Mangmang Shi, Xiaoyan Zhang
wiley +1 more source
Enhancing social participation in older adults with noncommunicable diseases: insights from system dynamics modeling. [PDF]
Liu C +5 more
europepmc +1 more source
Shapeshifting Liquid Metal Droplets for Soft Fluidic Machines
This study presented a liquid metal shape shifting strategy which harnesses Lorentz force, surface tension and fluid instabilities to achieve autonomous fluidic power. By using a liquid metal droplet as a mobile current carrier, this strategy enables the development of low‐voltage, self‐oscillating pumps that outperform existing soft pumps.
Saba Firouznia +5 more
wiley +1 more source

