Results 51 to 60 of about 7,920 (199)

Lauflumide (NLS-4) Is a New Potent Wake-Promoting Compound

Frontiers in Neuroscience, 2018
Psychostimulants are used for the treatment of excessive daytime sleepiness in a wide range of sleep disorders as well as in attention deficit hyperactivity disorder or cognitive impairment in neuropsychiatric disorders.
Gianina Luca, Gianina Luca, Mojtaba Bandarabadi, Eric Konofal, Michel Lecendreux, Michel Lecendreux, Laurent Ferrié, Bruno Figadère, Mehdi Tafti, Mehdi Tafti   +9 more
doaj   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Effect of peri‐operative pharmacological interventions on postoperative delirium in patients having cardiac surgery: a systematic review and Bayesian network meta‐analysis

Anaesthesia, Volume 81, Issue 2, Page 274-287, February 2026.
Summary Introduction Postoperative delirium is a common complication following cardiac surgery. Despite its known impact on patient outcomes, effective preventative strategies remain elusive. We aimed to perform a comprehensive Bayesian network meta‐analysis of randomised controlled trials assessing the effect of pharmacological interventions on the ...
Ivo Queiroz, Lucas M. Barbosa, Mariano Gallo Ruelas, Beatriz Araújo, Maria L. R. Defante, Arthur H. Tavares, Cynthia Florencio de Mesquita, Tulio Pimentel, Beatriz Ximenes Mendes, Iuri Ferreira Felix, André Rivera, Rafael Oliva Morgado Ferreira, Helen M. de Oliveira, Bruno B. Righetto, Nathan J. Smischney, Guangyu Tong, Daqing Ma   +16 more
wiley   +1 more source

Pharmacokinetics of Novel Dopamine Transporter Inhibitor CE-123 and Modafinil with a Focus on Central Nervous System Distribution [PDF]

, 2023
Iva Spreitzer, Josefin Keife, T. Strasser, Predrag Kalaba, Jana Lubec, Winfried Neuhaus, Gert Lübec, Thierry Langer, Judith Wackerlig, Irena Loryan   +9 more
openalex   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 44-59, January 2026.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn, Jee‐Young Lee, Giorgia Sciacca, Stacy Patterson, Adam Morton, Paul Pun, Walaa A. Kamel, Marina Picillo, Bart Post, Eng‐King Tan, Tamine Capato, Bastiaan R. Bloem, Manon Auffret, Annelien M. Oosterbaan, Willanka Kapelle, Michiko K. Bruno, Lorraine V. Kalia, Jeffrey H. Kordower, Daniela Berg   +18 more
wiley   +1 more source

The effect of modafinil on the rat dopamine transporter and dopamine receptors D1-D3 paralleling cognitive enhancement in the radial arm maze

Frontiers in Behavioral Neuroscience, 2015
A series of drugs have been reported to increase memory performance modulating the dopaminergic system and herein modafinil was tested for its working memory (WM) enhancing properties. Reuptake inhibition of dopamine, serotonin (SERT) and norepinephrine (
Yasemin eKarabacak, Sunetra eSase, Yogesh eAher, Ajinkya eSase, Sivaprakasam eSaroja, Ana eCicvaric, Harald eHoeger, Michael eBerger, Vasiliy eBakulev, Harald H Sitte, Johann eLeban, Francisco J Monje, Gert eLubec   +12 more
doaj   +1 more source

Cognitive enhancement effects of stimulants: a randomized controlled trial testing methylphenidate, modafinil, and caffeine [PDF]

, 2020
Dimitris Repantis, Leonore Bovy, Kathrin Ohla, Simone Kühn, Martin Dresler   +4 more
openalex   +1 more source

Feasibility of dried blood spot collection for caffeine pharmacokinetic studies in microgravity: Insights from parabolic flight campaigns

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 35-47, January 2026.
Abstract Aims Therapeutic drug monitoring for astronauts faces limitations in conventional blood sampling and sample management onboard the international space station. Here, we explore the feasibility of dried blood spot (DBS) collection during parabolic flights (PF) to overcome these constraints.
Audrey Derobertmasure, Li Shean Toh, Céline Verstuyft, Srboljub Lukic, Christelle De Sousa Carvalho, Raphaël Couronné, Marie Beauvalet, Stéphanie Chhun, Pierre Boutouyrie   +8 more
wiley   +1 more source

Behavioral Changes in Combination Therapy of Ethanol and Modafinil on rats Focal Cerebral Ischemia

Basic and Clinical Neuroscience, 2020
Introduction: Ethanol is considered as an effective agent in reducing brain stroke injury. In this study, we assessed the effects of modafinil along with ethanol as a combination therapy on behavioral function in Wistar rats.
Yusef Abbasi, Kazem Mousavizadeh, Ronak Shabani, Majid Katebi, Mehdi Mehdizadeh   +4 more
doaj  

Abstinence Alters Triple Network Dynamics in Moderate‐to‐Heavy Drinkers

Human Brain Mapping, Volume 46, Issue 18, 15 December 2025.
A hidden semi‐Markov model was used to investigate differences in the dynamics of brain states among moderate to heavy drinkers under two conditions: typical drinking and alcohol abstinence. The results demonstrated altered dynamics, including a reduced probability of transitioning to a state characterized by high salience network activation in the ...
Mohammadreza Khodaei, Hope Peterson‐Sockwell, Clayton C. McIntyre, Robert G. Lyday, Sean L. Simpson, Paul J. Laurienti, Heather M. Shappell   +6 more
wiley   +1 more source