Results 61 to 70 of about 7,733 (194)

NAc core lesion blocks modafinil-induced arousal.

open access: yes, 2013
A, B, E and F: Time course changes of wakefulness produced by i.p. administration of vehicle or modafinil (90 mg/kg). Each circle represents the hourly mean ± SEM. Arrows indicate the injection time (9 A.M.).
Zhi-Li Huang (306746)   +5 more
core   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

open access: yesChronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 100-112, June 2026.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy   +3 more
wiley   +1 more source

Modafinil and modafinil analogues: free radical mechanism of the eugeroic and cognitive enhancment effect

open access: yes, 2018
Evidence is presented that strongly implicates the involvement of free radical species in the eugeroic and cognitive enhancement ability of modafinil and modafinil-like analogues via a dissociative electron transfer (DET) or attachment mechanism ...
Fong, Clifford, W
core   +1 more source

Usage élargi du modafinil : quel risque addictif ?

open access: yes, 2008
Le modafinil est un psychostimulant commercialisé en France depuis 1994 sous le nom de Modiodal$^\circledR$. Son mécanisme d'action, différent de celui des amphétamines, repose sur une potentialisation de l'activité α-1-adrénergique cérébrale et sur l ...
Hélène Eysseric   +4 more
core   +1 more source

Attention‐deficit hyperactivity disorder in children and young persons during the COVID‐19 pandemic. A temporal trends analysis of electronic heath records in Greater Manchester, England

open access: yesJCPP Advances, Volume 6, Issue 2, June 2026.
Abstract Background The incidence of attention‐deficit hyperactivity disorder (ADHD) in children and young people has increased in recent years. Disease frequency varies according to sociodemographic characteristics. There are seasonal patterns in ADHD diagnosis and prescribing with rates falling during school holidays.
Louise Hussey   +7 more
wiley   +1 more source

Modafinil dependence: A case with attention-deficit/hyperactivity disorder

open access: yes, 2018
Modafinil is generally known as a drug with low addiction potential. There are few case reports in the literature demonstrating that Modafinil, stated being capable of diminishing symptoms of attention deficit/hyperactivity disorder (ADHD), causes ...
Tümkaya, Selim   +4 more
core   +1 more source

Lauflumide (NLS-4) Is a New Potent Wake-Promoting Compound

open access: yesFrontiers in Neuroscience, 2018
Psychostimulants are used for the treatment of excessive daytime sleepiness in a wide range of sleep disorders as well as in attention deficit hyperactivity disorder or cognitive impairment in neuropsychiatric disorders.
Gianina Luca   +9 more
doaj   +1 more source

Pharmacological Management, Safety, and Outcomes in Bipolar Disorder: An Integrated Narrative Review of Clinical and Translational Evidence

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
This graph summarizes bipolar disorder management, showing pharmacological treatments including lithium, valproate, antipsychotics, combination therapy, and emerging agents. It links these treatments to outcomes such as relapse reduction, mortality benefits, and cognitive effects, while highlighting safety issues, poor adherence, pregnancy risks, and ...
Gudisa Bereda
wiley   +1 more source

Modafinil improves monocrotaline-induced pulmonary hypertension rat model

open access: yes, 2020
BACKGROUND: Pulmonary arterial hypertension (PAH) progressively leads to increases in pulmonary vasoconstriction. Modafinil plays a role in vasorelaxation and blocking KCa3.1 channel with a result of elevating intracellular cyclic adenosine monophosphate
조민선   +3 more
core   +1 more source

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