Results 51 to 60 of about 7,733 (194)

Postmortem Evidence of CRH Neuron Reduction in Narcolepsy Without Cataplexy With Borderline Hypocretin‐1 Levels

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy is classified as type 1 (NT1) or type 2 (NT2) mainly according to hypocretin deficiency rather than cataplexy. While CRH neuron loss in the PVN has been described in NT1, it remains unclear whether similar changes occur in narcolepsy without cataplexy.
Ling Shan   +5 more
wiley   +1 more source

Effect of modafinil on simulated driving performance

open access: yes, 2012
Modafinil (2-[(diphenylmethyl)sulfinyl]acetamide, Modavigil¬¨vÜ) is a novel stimulant medication shown to improve alertness, cognitive performance and subjective mood.
Hartley, J (15927056)
core   +1 more source

Effects of Modafinil on Sleep Pattern during Methamphetamine Withdrawal: A Double-blind Randomized Controlled Trial [PDF]

open access: yesAddiction and Health, 2019
Background: Methamphetamine (MA) abuse is a serious and costly public health problem worldwide; It also commonly affects the sleep quality. The present study was carried out aiming to evaluate the effectiveness of modafinil versus placebo on sleep ...
Seyed Mohamad Moosavi   +2 more
doaj   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

open access: yesExperimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford   +4 more
wiley   +1 more source

Modafinil: A smart drug with psychiatric implications

open access: yes, 2017
IntroductionModafinil is approved to treat excessive somnolence but it is also off-spec used as a treatment for ADHD and as a cognitive enhancer. Research on the effects of modafinil on cognitive function have yielded mixed results.
L. Montes Reula   +7 more
core   +1 more source

Modafinil ameliorates excessive daytime sleepiness after traumatic brain injury [PDF]

open access: yes, 2010
BACKGROUND: Excessive daytime sleepiness (EDS) and fatigue are common symptoms after traumatic brain injury (TBI), but there is no specific treatment for affected patients.
Kaiser, P   +16 more
core   +1 more source

Effectiveness of Alcohol Use Disorder Pharmacotherapies by Sex: Systematic Review and Meta‐Analysis

open access: yesDrug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Issues Alcohol use disorder (AUD) shows sex‐related differences in prevalence, harm and treatment response. Despite growing interest in sex differences, evidence synthesis evaluating pharmacotherapy effectiveness by sex remains limited. Approach Web of Science, PubMed, Scopus, PsycINFO and Cochrane were searched twice.
Juliette Allen   +11 more
wiley   +1 more source

Hypothalamic Arousal Regions Are Activated during Modafinil-Induced Wakefulness

open access: yes, 2000
Modafinil is an increasingly popular wake-promoting drug used for the treatment of narcolepsy, but its precise mechanism of action is unknown. To determine potential pathways via which modafinil acts, we administered a range of doses of modafinil to rats,
Thomas E. Scammell   +6 more
core   +1 more source

The Issue of “Smart Drugs” on the Example of Modafinil: Toxicological Analysis of Evidences and Biological Samples

open access: yesJournal of Xenobiotics
Cognitive enhancement through stimulants such as modafinil is becoming increasingly popular, with many individuals using prescription stimulants for non-medical purposes to improve alertness, attention, and mood.
Karolina Nowak   +3 more
doaj   +1 more source

Ion‐Pairing and Counterion Effects in Contemporary Photochemistry

open access: yesAngewandte Chemie Novit, Volume 2, Issue 2, June 2026.
Ion‐pairing and counterion effects have emerged as fundamental yet underexplored determinants of photochemical behavior. Far from inert, counterions, and Coulombic interactions modulate excited‐state dynamics, quenching efficiencies, emission, and catalytic pathways.
Matthias Schmitz, Christoph Kerzig
wiley   +1 more source

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