Results 51 to 60 of about 8,589 (193)

A Quantitative Analysis of Street‐Level Drugs Seized in New South Wales, Australia: Purity, Dose and Adulterants

Drug and Alcohol Review, Volume 45, Issue 7, November 2026.
ABSTRACT Introduction The Combined Surveillance and Monitoring of Seized Samples (CoSMoSS) program is a joint harm reduction initiative between NSW Health and NSW Police Force. Here, we examine the contents and purity of a sample of seized suspected target drugs (cocaine, heroin, methamphetamine and 3,4‐methylenedioxymethamphetamine ‘MDMA’).
Janette L. Smith, Christine A. Harvey, NSW Police Force, Christopher J. Ewers, Kelsey E. Seyfang, Emily D. Bottero, Jared A. Brown, Thanjira Jiranantakan   +7 more
wiley   +1 more source

High Potency Eugeroics-- Wake-Promoting Agents Beyond Modafinil [PDF]

, 2015
Modafinil (Provigil) belongs to a new pharmaceutical class known as eugeroics— wake-promoting agents. Directly enhancing conductance across neuronal membranes, modafinil, amplifies presynaptic Na/Ca influx; resultant widespread depolarization of cortical
Yoham, Joseph
core  

Armodafinil versus Modafinil in Patients of Excessive Sleepiness Associated with Shift Work Sleep Disorder: A Randomized Double Blind Multicentric Clinical Trial

Neurology Research International, 2011
Aim. To compare the efficacy and safety of armodafinil, the R-enantiomer of modafinil, with modafinil in patients of shift work sleep disorder (SWSD). Material and Methods. This was a 12-week, randomized, comparative, double-blind, multicentric, parallel-
D. V. Tembe, A. Dhavale, H. Desai, D. N. Mane, S. K. Raut, G. Dhingra, U. Sardesai, S. Saoji, M. Rohra, V. G. Shinde, M. Padsalge, A. Paliwal, K. Abbasi, P. Devnani, S. Papinwar, S. Phadke, H. Mehta, V. Bhailume   +17 more
doaj   +1 more source

Effects of Modafinil on Sleep Pattern during Methamphetamine Withdrawal: A Double-blind Randomized Controlled Trial [PDF]

Addiction and Health, 2019
Background: Methamphetamine (MA) abuse is a serious and costly public health problem worldwide; It also commonly affects the sleep quality. The present study was carried out aiming to evaluate the effectiveness of modafinil versus placebo on sleep ...
Seyed Mohamad Moosavi, Jamshid Yazdani-Charati, Fatemeh Amini   +2 more
doaj   +1 more source

Long‐Term Treatment Patterns in Norwegian ADHD‐Medicine Users: A Cohort Register‐Based Study With 5 Years of Follow‐Up, 2012–2021

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose To improve interpretation of long‐term ADHD medication treatment trajectories in Norway by examining sex‐ and age‐specific persistence, distinguishing within‐substance product switching from active‐ingredient (ATC substance) switching, and describing the medication and prescriber context of the last observed dispensation before non ...
Espen Anker, Anne Halmøy, Mats Fredriksen   +2 more
wiley   +1 more source

Modafinil ameliorates excessive daytime sleepiness after traumatic brain injury [PDF]

, 2010
BACKGROUND: Excessive daytime sleepiness (EDS) and fatigue are common symptoms after traumatic brain injury (TBI), but there is no specific treatment for affected patients.
Kaiser, P, E. Werth, R. Stocker, Kaiser, P R, Stocker, R, Bassetti, C L, J. Thomann, Baumann, C R, C. L. Bassetti, Thomann, J, C. R. Baumann, Meier, J, P. R. Kaiser, Werth, E; https://orcid.org/, P. O. Valko, Valko, P O, J. Meier, Werth E, Bassetti CL, Baumann CR, Thomann J, Meier J, Valko PO, Stocker R, Kaiser PR   +24 more
core   +1 more source

COVID‐19–Induced Narcolepsy Type I With Cataplexy: A Short Report

Journal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Narcolepsy type I is a rare neurological sleep disorder characterised by chronic excessive daytime sleepiness, cataplexy, and low orexin (hypocretin) levels. Infection with SARS‐CoV‐2 has been linked to neurological and neuropsychiatric sequelae, but cases of post‐COVID narcolepsy remain extremely uncommon.
Torsten Vinding Merinder, Martin Langeskov‐Christensen, Filip Kirov   +2 more
wiley   +1 more source

Impact of Astroglial Connexins on Modafinil Pharmacological Properties

, 2016
International audienceSTUDY OBJECTIVES:Modafinil is a non-amphetaminic wake-promoting compound used as therapy against sleepiness and narcolepsy. Its mode of action is complex, but modafinil has been recently proposed to act as a cellular-coupling ...
Dauvilliers, Yves, M, Piérard, Christophe, Dauvilliers, Yves,, Mouthon, Franck, Chauveau, Frédéric, Liu, Xinhe, Lin, Jian-Sheng, Thomasson, Julien, Lagarde, Didier, Giaume, Christian, Charvériat, Mathieu, Perier, Magali, Duchêne, Adeline, Zhao, Yan, Jeanson, Tiffany, Picoli, Christèle   +15 more
core   +1 more source

The Issue of “Smart Drugs” on the Example of Modafinil: Toxicological Analysis of Evidences and Biological Samples

Journal of Xenobiotics
Cognitive enhancement through stimulants such as modafinil is becoming increasingly popular, with many individuals using prescription stimulants for non-medical purposes to improve alertness, attention, and mood.
Karolina Nowak, Agnieszka Chłopaś-Konowałek, Paweł Szpot, Marcin Zawadzki   +3 more
doaj   +1 more source

Postmortem Evidence of CRH Neuron Reduction in Narcolepsy Without Cataplexy With Borderline Hypocretin‐1 Levels

Journal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Narcolepsy is classified as type 1 (NT1) or type 2 (NT2) mainly according to hypocretin deficiency rather than cataplexy. While CRH neuron loss in the PVN has been described in NT1, it remains unclear whether similar changes occur in narcolepsy without cataplexy.
Ling Shan, Suzan Linssen, Rolf Fronczek, Lucie Barateau, Christelle Peyron, Yves Dauvilliers   +5 more
wiley   +1 more source