Results 31 to 40 of about 7,733 (194)
Journal of Pharmacy & Pharmaceutical Sciences, 2010 Purpose. The pharmacokinetics of modafinil were investigated in relation to gender and ethnicity in healthy young volunteers from Han, Mongolian, Korean, Uygur and Hui ( n = 10/group) following administration of a single 200 mg oral dose. Methods.
Tao Guo, Longshan Zhao, Dong-Ya Xia
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Modafinil abrogates methamphetamine-induced neuroinflammation and apoptotic effects in the mouse striatum. [PDF]
PLoS ONE, 2012 Methamphetamine is a drug of abuse that can cause neurotoxic damage in humans and animals. Modafinil, a wake-promoting compound approved for the treatment of sleeping disorders, is being prescribed off label for the treatment of methamphetamine ...
Mariana Raineri +7 more
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The role of nucleus accumbens core/shell in sleep-wake regulation and their involvement in modafinil-induced arousal. [PDF]
PLoS ONE, 2012 BACKGROUND: We have previously shown that modafinil promotes wakefulness via dopamine receptor D(1) and D(2) receptors; however, the locus where dopamine acts has not been identified. We proposed that the nucleus accumbens (NAc) that receives the ventral
Mei-Hong Qiu +5 more
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Modafinil does not reduce cocaine use in methadone-maintained individuals
Drug and Alcohol Dependence Reports, 2022 Introduction: There are no approved medications for the treatment of cocaine use disorder (CUD). Modafinil, a cognitive-enhancer with weak stimulant-like effects, has shown promise in initial studies as a treatment for CUD. Its potential efficacy has not
Elise E. DeVito +5 more
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Bioethical issues on modafinil [PDF]
, 2016 En este artículo se analiza la mejora de la cognición por el modafinilo, un eugeroico -estimulante beneficioso-, que aumenta los estados de vigilia y que, además, es considerado el primer fármaco que merece la denominación de nootrópico.
García Díaz, Paloma
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Comparison of modafinil and pitolisant in narcolepsy: a non-inferiority metaanalytical approach
Drugs in Context, 2020 Aim: To assess the non-inferiority of pitolisant, a new compound for the relief of excessive daytime sleepiness (EDS) and cataplexy in narcolepsy, compared with modafinil.
Philippe Lehert, Cassandra Szoeke
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Modafinil for psychostimulant dependence
, 2008 Psychostimulant dependence is a major public health issue in many parts of the world associated with a wide range of psychological, medical and social problems.
Shearer, James Douglas
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Journal of Applied Toxicology, EarlyView.ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado +9 more
wiley +1 more source
Modafinil modulation of the default mode network [PDF]
, 2010 RationaleThe default mode network (DMN) is a functional network which is implicated in a range of cognitive processes. This network is proposed to consist of hubs located in the ventromedial prefrontal cortex (vmPFC), posterior cingulate/retrosplenial ...
Jong H. Yoon +5 more
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PM&R, EarlyView.Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen +7 more
wiley +1 more source