Results 21 to 30 of about 7,733 (194)

Modafinil’s effects on cognition and sleep quality in affectively-stable patients with bipolar disorder: a pilot study

open access: yesFrontiers in Psychiatry, 2023
IntroductionDespite advances in the treatment of bipolar disorder (BD), most patients do not achieve complete inter-episode recovery and functional disability is common.
Jessica M. Lipschitz   +11 more
doaj   +1 more source

Effects of Modafinil on Behavioral Learning and Hippocampal Synaptic Transmission in Rats [PDF]

open access: yesInternational Neurourology Journal, 2015
Purpose: Modafinil is a wake-promoting agent that has been proposed to improve cognitive performance at the preclinical and clinical levels. Since there is insufficient evidence for modafinil to be regarded as a cognitive enhancer, the aim of this study ...
Wen-Wen Yan   +7 more
doaj   +1 more source

Efficacy of modafinil on fatigue and excessive daytime sleepiness associated with neurological disorders: a systematic review and meta-analysis.

open access: yesPLoS ONE, 2013
BackgroundModafinil is a novel wake-promoting agent approved by the FDA ameliorating excessive daytime sleepiness (EDS) in three disorders: narcolepsy, shift work sleep disorder and obstructive sleep apnea.
Ping Sheng   +7 more
doaj   +1 more source

Roles of adrenergic α1 and dopamine D1 and D2 receptors in the mediation of the desynchronization effects of modafinil in a mouse EEG synchronization model. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Synchronized electroencephalogram (EEG) activity is observed in pathological stages of cognitive impairment and epilepsy. Modafinil, known to increase the release of catecholamines, is a potent wake-promoting agent, and has shown some ...
Chang-Rui Chen   +5 more
doaj   +1 more source

Being Limitless: A Discursive Analysis of Online Accounts of Modafinil Use

open access: yes, 2020
Modafinil is a prescription-only substance in the UK for the treatment of disorders such as narcolepsy. Soldiers have also used this substance as an alternative to amphetamines in situations where they face long periods of sleep deprivation.
Forshaw, Mark; id_orcid   +6 more
core   +1 more source

Participation of Dopamine D1 and D2 Receptors in the Rapid-Onset Behavioral Sensitization to Modafinil

open access: yesFrontiers in Pharmacology, 2019
Studies on the abuse potential of modafinil, a psychostimulant-like drug used to treat narcolepsy, are still controversial. While some studies claim no potential for abuse, increasing evidence suggests that modafinil induces abuse-related effects ...
Raphael Wuo-Silva   +12 more
doaj   +1 more source

High resolution mapping of modafinil induced changes in glutamate level in rat brain. [PDF]

open access: yesPLoS ONE, 2014
Modafinil is marketed in the United States for the treatment of narcolepsy and daytime somnolence due to shift-work or sleep apnea. Investigations of this drug in the treatment of cocaine and nicotine dependence in addition to disorders of executive ...
Mohammad Haris   +9 more
doaj   +1 more source

Frequency of modafinil use and means for both benefits and risks of modafinil.

open access: yes, 2020
Frequency of modafinil use and means for both benefits and risks of modafinil.
Nicola Rycroft (8407251)   +2 more
core   +1 more source

The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors. [PDF]

open access: yesPLoS ONE, 2011
Modafinil is a mild psychostimulant with pro-cognitive and antidepressant effects. Unlike many conventional stimulants, modafinil has little appreciable potential for abuse, making it a promising therapeutic agent for cocaine addiction.
Kyle C Schmitt, Maarten E A Reith
doaj   +1 more source

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