Modafinil-induced Fixed Drug Eruption
Modafinil is a stimulant drug widely used to promote wakefulness in a variety of psychiatric and neurological conditions. Modafinil-induced severe dermatologic reactions are uncommon but serious side effects.
Girish Vasant Gaikwad +1 more
doaj +2 more sources
MODAFINIL INDUCES RAPID-ONSET BEHAVIORAL SENSITIZATION AND CROSS-SENSTIZATION WITH COCAINE IN MICE: IMPLICATIONS FOR THE ADDICTIVE POTENTIAL OF MODAFINIL [PDF]
There is substantial controversy about the addictive potential of modafinil, a wake-promoting drug used to treat narcolepsy, proposed as pharmacotherapy for cocaine abuse, and used indiscriminately by healthy individuals due to its positive effects on ...
Raphael Wuo-Silva +17 more
doaj +3 more sources
Modafinil Induced Psychosis in a Patient with Bipolar 1 Depression
Modafinil has been used as an adjunctive medication in the treatment of bipolar 1 depression with reported success. Case reports have been published demonstrating modafinil induced mania in bipolar patients and modafinil induced psychosis in ...
Alexander A. DiSciullo +2 more
doaj +2 more sources
Modafinil as a catecholaminergic agent: empirical evidence and unanswered questions
Modafinil, in its two clinical formulations (Provigil® and Nuvigil®), is a widely prescribed wake-promoting therapeutic agent. It binds competitively to the cell membrane dopamine transporter and is dependent on catecholaminergic (dopaminergic ...
Jonathan P Wisor
doaj +2 more sources
Gender Representations in Online Modafinil Markets [PDF]
This chapter examines representations of gender in online modafinil markets. While gender has often been absent from scholarship on online drug markets, our analysis demonstrates the ubiquity of gender in representations of modafinil users and sellers ...
Chatwin, Caroline, Fleetwood, Jennifer
core +3 more sources
Lessons Learned From a Delayed-Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease. [PDF]
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Virmani T +8 more
europepmc +2 more sources
An adolescent hospitalised after polysubstance abuse: A case report. [PDF]
General Psychiatry, Volume 39, Issue 3, June 2026.
Zhang H, Yi J, Yu X.
europepmc +2 more sources
Modafinil Reduces Neuronal Pyroptosis and Cognitive Decline After Sleep Deprivation
Sleep deprivation (SD) induces systemic inflammation that promotes neuronal pyroptosis. The purpose of this study was to investigate the effect of an antioxidant modafinil on neuronal pyroptosis and cognitive decline following SD.
Xiangyang Xiong +16 more
doaj +1 more source
Treatment with dopaminergic agents result excessive daytime sleepiness (EDS) and some studies have shown the benefit of using modafinil for treating excessive daytime sleepiness of Parkinson's disease (PD) patient.
Rina Ando +9 more
doaj +1 more source
Modafinil Improves Catalepsy in a Rat 6-Hydroxydopamine Model of Parkinson’s Disease; Possible Involvement of Dopaminergic Neurotransmission [PDF]
Purpose: Modafinil is a vigilance-enhancing drug licensed for narcolepsy. The use of modafinil leads to various neuromodulatory effects with very low abuse potential. A body of evidence suggested that modafinil may have anti-parkinsonian effects.
Reza Vajdi-Hokmabad +4 more
doaj +1 more source

