Results 11 to 20 of about 6,043 (157)
Modafinil Reduces Neuronal Pyroptosis and Cognitive Decline After Sleep Deprivation
Frontiers in Neuroscience, 2022 Sleep deprivation (SD) induces systemic inflammation that promotes neuronal pyroptosis. The purpose of this study was to investigate the effect of an antioxidant modafinil on neuronal pyroptosis and cognitive decline following SD.
Xiangyang Xiong +16 more
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Journal of Pharmacological Sciences, 2018 Treatment with dopaminergic agents result excessive daytime sleepiness (EDS) and some studies have shown the benefit of using modafinil for treating excessive daytime sleepiness of Parkinson's disease (PD) patient.
Rina Ando +9 more
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Modafinil Improves Catalepsy in a Rat 6-Hydroxydopamine Model of Parkinson’s Disease; Possible Involvement of Dopaminergic Neurotransmission [PDF]
Advanced Pharmaceutical Bulletin, 2017 Purpose: Modafinil is a vigilance-enhancing drug licensed for narcolepsy. The use of modafinil leads to various neuromodulatory effects with very low abuse potential. A body of evidence suggested that modafinil may have anti-parkinsonian effects.
Reza Vajdi-Hokmabad +4 more
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Frontiers in Psychiatry, 2023 IntroductionDespite advances in the treatment of bipolar disorder (BD), most patients do not achieve complete inter-episode recovery and functional disability is common.
Jessica M. Lipschitz +11 more
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Effects of Modafinil on Behavioral Learning and Hippocampal Synaptic Transmission in Rats [PDF]
International Neurourology Journal, 2015 Purpose: Modafinil is a wake-promoting agent that has been proposed to improve cognitive performance at the preclinical and clinical levels. Since there is insufficient evidence for modafinil to be regarded as a cognitive enhancer, the aim of this study ...
Wen-Wen Yan +7 more
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PLoS ONE, 2013 BackgroundModafinil is a novel wake-promoting agent approved by the FDA ameliorating excessive daytime sleepiness (EDS) in three disorders: narcolepsy, shift work sleep disorder and obstructive sleep apnea.
Ping Sheng +7 more
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Modafinil-induced Fixed Drug Eruption
Indian Journal of Psychological Medicine, 2012 Modafinil is a stimulant drug widely used to promote wakefulness in a variety of psychiatric and neurological conditions. Modafinil-induced severe dermatologic reactions are uncommon but serious side effects.
Girish Vasant Gaikwad +1 more
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Roles of adrenergic α1 and dopamine D1 and D2 receptors in the mediation of the desynchronization effects of modafinil in a mouse EEG synchronization model. [PDF]
PLoS ONE, 2013 BACKGROUND: Synchronized electroencephalogram (EEG) activity is observed in pathological stages of cognitive impairment and epilepsy. Modafinil, known to increase the release of catecholamines, is a potent wake-promoting agent, and has shown some ...
Chang-Rui Chen +5 more
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Frontiers in Pharmacology, 2016 There is substantial controversy about the addictive potential of modafinil, a wake-promoting drug used to treat narcolepsy, proposed as pharmacotherapy for cocaine abuse, and used indiscriminately by healthy individuals due to its positive effects on ...
Raphael Wuo-Silva +17 more
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High resolution mapping of modafinil induced changes in glutamate level in rat brain. [PDF]
PLoS ONE, 2014 Modafinil is marketed in the United States for the treatment of narcolepsy and daytime somnolence due to shift-work or sleep apnea. Investigations of this drug in the treatment of cocaine and nicotine dependence in addition to disorders of executive ...
Mohammad Haris +9 more
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