Results 61 to 70 of about 7,920 (199)

Narcolepsy: Pathophysiology, Diagnosis, Management, and Future Directions, a Narrative Review

Brain and Behavior, Volume 15, Issue 12, December 2025.
This visual summary outlines the pathophysiology of narcolepsy, driven by hypocretin loss, and details its clinical diagnosis, current management strategies, and the shift toward future disease‐modifying therapies like orexin agonists and immunomodulation.
Natasha Elaine Hastings, Khalil El Abdi, Fazeela Bibi, Bilal Aslam, Milka Rosario Nuñez, Muhammad Tahla Rehman Sherani, Sujeet Shadmani, Umama Alam, Vohra Maham Hassan, Hoor‐e‐Ainaa, Hania Imran, James Hanna, Said Hamid Sadat   +12 more
wiley   +1 more source

Modafinil #259 [PDF]

Journal of Palliative Medicine, 2012
Jennifer, Cheng, Hunter, Groninger
openaire   +2 more sources

Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation

Frontiers in Cellular Neuroscience, 2018
Background: Sleep deprivation (SD) plagues modern society due to the professional demands. It prevails in patients with mood and neuroinflammatory disorders.
Meetu Wadhwa, Garima Chauhan, Koustav Roy, Surajit Sahu, Satyanarayan Deep, Vishal Jain, Krishna Kishore, Koushik Ray, Lalan Thakur, Usha Panjwani   +9 more
doaj   +1 more source

Armodafinil and modafinil in the treatment of cancer-related fatigue: A systematic review

Annals of Oncology Research and Therapy
Cancer-related fatigue (CRF) is often cited as the most common and most severe symptom faced by cancer patients, whether that be before they receive a diagnosis of cancer or many years after cessation of cancer therapy or cancer remission.
Alexa Mcguinness
doaj   +1 more source

Short- and Long-Term Efficacy of Modafinil at Improving Quality of Life in Stroke Survivors: A Post Hoc Sub Study of the Modafinil in Debilitating Fatigue After Stroke Trial

Frontiers in Neurology, 2018
BackgroundThe phase-II modafinil in debilitating fatigue after stroke trial demonstrated that modafinil improves fatigue and quality of life in severely fatigued stroke survivors.
Thomas P. Lillicrap, Thomas P. Lillicrap, Christopher R. Levi, Christopher R. Levi, Elizabeth Holliday, Mark William Parsons, Mark William Parsons, Andrew Bivard, Andrew Bivard   +8 more
doaj   +1 more source

Efficacy of modafinil compared to γ-hydroxybutyrate in the treatment of narcolepsy

, 2023
Aaron L. Kennedy, Andrew J. Boileau
openalex   +1 more source

The use of modafinil for the treatment of fatigue in multiple sclerosis: A systematic review and meta‐analysis of controlled clinical trials

Brain and Behavior
Introduction Multiple sclerosis (MS) is a debilitating neurological condition affecting nearly one million people across the United States. Among the most prominent symptoms of the condition are excessive fatigue and daytime sleepiness. Numerous clinical
Shamas Ghazanfar, Minaam Farooq, Shurjeel Uddin Qazi, Bipin Chaurasia, Ulrike Kaunzner   +4 more
doaj   +1 more source

Comparative efficacy, safety and benefit/risk of alerting agents for excessive daytime sleepiness in patients with obstructive sleep apnoea: a network meta-analysisResearch in context

EClinicalMedicine
Summary: Background: Obstructive sleep apnoea (OSA) is a common chronic respiratory disease associated with a high burden of disabilities related to sleepiness and reduced quality of life.
Jean-Louis Pépin, Philippe Lehert, Raoua Ben Messaoud, Marie Joyeux-Faure, Christian Caussé, Jerryll Asin, Ferran Barbé, Maria R. Bonsignore, Winfried Randerath, Johan Verbraecken, Sonya Craig, Yves Dauvilliers   +11 more
doaj   +1 more source

Cataplexy as a side effect of modafinil in a patient without narcolepsy

Sleep Science, 2014
Narcolepsy is a disease in which there is diurnal excessive sleepiness with sleep attacks and a prevalence in the general population of 1/4000 individuals.
Eduardo Lopes, Danielle Pereira, Nilce Sanny Costa da Silva Behrens, Hassana de Almeida Fonseca, Paola Oliveira Calvancanti, Taís Figueiredo de Araújo Lima, Marcia Pradella-Hallinan, Juliana Castro, Sergio Tufik, Fernando Morgadinho Santos Coelho   +9 more
doaj   +1 more source

Identification of adrafinil and its main metabolite modafinil in human hair. Self-administration study and interpretation of an authentic case [PDF]

, 2020
Alice Ameline, Laurie Gheddar, Jean‐Sébastien Raul, Pascal Kintz   +3 more
openalex   +1 more source