Results 101 to 110 of about 2,484,152 (338)

EANN: Event Adversarial Neural Networks for Multi-Modal Fake News Detection

open access: yesKnowledge Discovery and Data Mining, 2018
As news reading on social media becomes more and more popular, fake news becomes a major issue concerning the public and government. The fake news can take advantage of multimedia content to mislead readers and get dissemination, which can cause negative
Yaqing Wang   +7 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Modal Noise Mitigation through Fiber Agitation for Fiber-fed Radial Velocity Spectrographs

open access: yes, 2018
Optical fiber modal noise is a limiting factor for high precision spectroscopy signal-to-noise in the near-infrared and visible. Unabated, especially when using highly coherent light sources for wavelength calibration, modal noise can induce radial ...
Eggerman, Dominic   +6 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Research on Modal Enhancement of EMU Vehicle Carbody Structure Based on Sensitivity Analysis

open access: yesChengshi guidao jiaotong yanjiu
Objective To comprehensively understand the influence of carbody component dimensions on carbody modal characteristics, a sensitivity analysis of EMU (electric multiple units) body modal is conducted to enhance the main vibration frequency of carbody ...
DU Yanpin   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Analysis of Vibration Characteristics and Influencing Factors of Complex Tread Pattern Tires Based on Finite Element Method

open access: yesMachines
The vibration of the tires significantly impacts a vehicle’s ride comfort and noise level; however, the current analysis of tire vibration characteristics often involves excessive simplification in their models, leading to a reduction in model accuracy ...
Mengdi Xu   +3 more
doaj   +1 more source

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