FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang +11 more
wiley +1 more source
On the Effect of Intra- and Inter-Node Sampling Variability on Operational Modal Parameters in a Digital MEMS-Based Accelerometer Sensor Network for SHM: A Preliminary Numerical Investigation. [PDF]
Brambilla M, Chiariotti P, Cigada A.
europepmc +1 more source
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang +12 more
wiley +1 more source
A Multimodal Hybrid Piezoelectric-Electromagnetic Vibration Energy Harvester Exploiting the First and Second Resonance Modes for Broadband Low-Frequency Applications. [PDF]
Shishkovski D +5 more
europepmc +1 more source
This work overcomes the long‐standing challenge of hydrophilic modification of silicone rubber via a gradient polarity modification strategy. By constructing a hydrophilic interpenetrating network within cured SR, simultaneous surface‐to‐bulk modification is achieved while enabling monitoring through a Eu3+ complex fluorescent tracer.
Lihui Zhang +11 more
wiley +1 more source
Experimental realization of logical elastic bits as qubit analogues in a nonlinear oscillator. [PDF]
Mahmood KT +5 more
europepmc +1 more source
Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang +10 more
wiley +1 more source
Human body dynamics simulation and comfort evaluation of interhospital transport patients with different road conditions. [PDF]
Yao M +7 more
europepmc +1 more source
Impedance‐Matched High‐Overtone Thickness‐Shear Bulk Acoustic Resonators With Scalable Mode Volume
A bottom‐electrode‐free high‐overtone bulk acoustic resonator is achieved by lateral excitation of antisymmetric thickness‐shear modes on a lithium‐niobate‐on‐silicon platform. Planar electrode geometry eliminates conventional loading along the resonance path and confines acoustic energy within the electrode gap.
Zi‐Dong Zhang +7 more
wiley +1 more source

