Results 111 to 120 of about 4,075,278 (310)

On the Development of an AI-Based Tool to Assess the Instantaneous Modal Properties of Nonlinear SDOF Systems

Applied Sciences
In this article, a data-driven algorithm is developed to assess the natural frequency and damping ratio of a nonlinear oscillating single-degree-of-freedom (SDOF) system.
Alvaro Iglesias-Pordomingo, Guillermo Fernandez, Alvaro Magdaleno, Antolin Lorenzana   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Consistent cross-modal identification of cortical neurons with coupled autoencoders. [PDF]

Nat Comput Sci, 2021
Gala R, Budzillo A, Baftizadeh F, Miller J, Gouwens N, Arkhipov A, Murphy G, Tasic B, Zeng H, Hawrylycz M, Sümbül U.   +10 more
europepmc   +1 more source

Modality Unified Attack for Omni-Modality Person Re-Identification

IEEE Transactions on Information Forensics and Security
9 pages,3 ...
Yuan Bian, Min Liu, Yunqi Yi, Xueping Wang, Yunfeng Ma, Yaonan Wang   +5 more
openaire   +2 more sources

Shared micromobility-driven modal identification of urban bridges

Automation in Construction, 2021
Said Quqa, P. Giordano, M. Limongelli
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Modal Measurements and Model Corrections of A Large Stroke Compliant Mechanism

Archive of Mechanical Engineering, 2014
In modelling flexure based mechanisms, generally flexures are modelled perfectly aligned and nominal values are assumed for the dimensions. To test the validity of these assumptions for a two Degrees Of Freedom (DOF) large stroke compliant mechanism ...
Wijma W., Boer S.E., Aarts R.G.K.M., Brouwer D.M., Hakvoort W.B.J.   +4 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Multi-Mode Recognition Method for Broadband Oscillation Based on Compressed Sensing and EEMD

Applied Sciences
In power systems, the application of wind power generation equipment and power electronic devices leads to an increased frequency of broadband oscillation events, and the detection of oscillation information becomes extremely difficult, due to the ...
Jinggeng Gao, Honglei Xu, Yong Yang, Haoming Niu, Jinping Liang, Haiying Dong   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source