Results 71 to 80 of about 308,109 (309)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Perspectives of Second-Order Blind Identification for Operational Modal Analysis of Civil Structures
Shock and Vibration, 2014 Innovative methods for output-only estimation of the modal properties of civil structures are based on blind source separation techniques. In the present paper attention is focused on the second-order blind identification (SOBI) algorithm and the ...
C. Rainieri
doaj +1 more source
Analysis of HOM interaction between cavities by multi-modal s-parameter measurements [PDF]
, 2005 Accelerating cavities exchange HOM power through interconnecting beam pipes in case of signal frequencies above the cut-off of their propagating waveguide modes.
Glock, Hans-Walter +3 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Impact Analysis of Modal Parameters of Marine Riser Based on Differential Transformation Method
Shiyou jixie, 2018 To study the change rule of modal parameters (natural frequency and vibration mode) of marine risers influenced by structural parameters (riser length and bending stiffness), axial tension (constant tension and variable tension), elastic restraint ...
Chen Wenli +3 more
doaj
Cross-modal Recurrent Models for Weight Objective Prediction from Multimodal Time-series Data
, 2017 We analyse multimodal time-series data corresponding to weight, sleep and steps measurements. We focus on predicting whether a user will successfully achieve his/her weight objective.
Bellahsen, Otmane +8 more
core +1 more source
Estimation of Modal Parameters and their Uncertainties [PDF]
, 1999 In this paper it is shown how to estimate the modal parameters as well as their uncertainties using the prediction error method of a dynamic system on the basis of uotput measurements only. The estimation scheme is assessed by means of a simulation study.
Andersen, P., Brincker, Rune
openaire
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source