Results 41 to 50 of about 4,754,074 (251)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Operational Modal Analysis for Seismic Protection of Structures [PDF]

open access: yes, 2008
This thesis focuses on output-only modal identification tests and on the opportunities they provide in the field of seismic protection of structures. The problem of a good measurement process, in order to obtain high quality data and reliable results ...
Rainieri, Carlo
core   +1 more source

Modal Parameters Estimation of Circular Plates Manufactured by FDM Technique Using Vibrometry: A Comparative Study

open access: yesApplied Sciences
This paper presents a comparative study focused on a modal parameters estimation of specimens manufactured by the FDM technique using a fixed embedded vibrometer based on the laser Doppler principle and roving hammer-impact method.
Martin Hagara   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modal Passport Concept for Enhanced Non-Destructive Monitoring and Diagnostics of Wind Turbine Blades

open access: yesNDT - Journal of Non-Destructive Testing
One of the most sensitive parts of a wind turbine to environmental influences are the rotating blades. Today, there are many technologies available to assess blade condition, but they all need to be developed to become more cost-effective and more ...
Aleksey Mironov   +2 more
doaj   +1 more source

Improved Modal Assurance Criterion using a quantification of identification errors per mode/sensor [PDF]

open access: yes, 2014
Scanning laser vibrometer measurements generate detailed maps of modal characteristics in normal or 3D directions. Since many points are measured, individual validation of cannot be performed manually in a reasonable time frame and a notable fraction of ...
BALMES, Etienne   +2 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Identification methods of floor void of sluice on soft foundation based on theory of modal flexibility

open access: yesShuili Shuiyun Gongcheng Xuebao, 2022
The sluice built on the soft soil foundation is prone to problems such as uneven foundation settlement and seepage deformation, which will induce disasters such as the sluice floor void.
LI Huokun   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Modal parameters prediction for robotic milling based on Gaussian process regression

open access: yesHangkong gongcheng jinzhan
The acquisition of the frequency response function of the robotic structure and the identification of dynam ic parameters have a significant impact on the prediction of robotic milling,and modal parameters have strong posture-dependence.
WAN Min   +3 more
doaj   +1 more source

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