Results 51 to 60 of about 534,974 (269)

Effectiveness of a structured emotional literacy and stress management program for female heads of household: a two-year longitudinal study in Cartagena, Colombia, and Valencia, Venezuela

Critical Public Health
Female heads of household face unique stressors related to economic survival and family care, yet few evidence-based interventions address their specific emotional health needs.
Heidy Rico, Mario de la Puente, Florentino Rico, Tatiana Londoño   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Multimodal integration of spatial information: The influence of object-related factors and self-reported strategies

Frontiers in Psychology, 2016
Spatial representations are a result of multisensory information integration. More recent findings suggest that the multisensory information processing of a scene can be facilitated when paired with a semantically congruent auditory signal.
Harun Karimpur, Kai Hamburger
doaj   +1 more source

Changing Modalities

Journal of Logic and Computation, 2004
The paper is devoted to an investigation of properties of dynamic modal logics with some interesting and rich features. A dynamic modal logic DML and its extension \(\mu\)DML are presented. They were developed in order to unify and extend dynamic epistemic logics proposed before in another paper by the author.
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Super phantoms: advanced models for testing medical imaging technologies

Communications Engineering
Phantoms are test objects used for initial testing and optimization of medical imaging techniques, but these rarely capture the complex properties of the tissue.
Srirang Manohar, Ioannis Sechopoulos, Mark A. Anastasio, Lena Maier-Hein, Rajiv (Raj) Gupta   +4 more
doaj   +1 more source

Feasibility of Laser Speckle-Based Perfusion Imaging in an Ex-Vivo Liver Model

IEEE Journal of Translational Engineering in Health and Medicine
Objective: Advancing microcirculatory perfusion assessment methods is crucial for evaluating organ status during ex-vivo organ preservation and expanding the donor pool.
Ata Chizari, Jan L. van der Hoek, Anne R. D. Rook, Marleen E. Krommendijk, Tess J. Snoeijink, Adrie Visser, Tom Knop, Jutta Arens, Srirang Manohar, Wiendelt Steenbergen, Erik Groot Jebbink   +10 more
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Modes on the Move: Interval Cycles and the Emergence of Major-Minor Tonality

Empirical Musicology Review, 2011
The issue of the emergence of major-minor tonality is addressed by recourse to a novel pitch grouping process, referred to as interval cycle proximity (ICP).
Matthew Woolhouse
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source