Results 81 to 90 of about 25,016 (264)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A Comparative Study of Voltage, Peak Current and Dual Current Mode Control Methods for Noninverting Buck-Boost Converter

Telfor Journal, 2016
This paper presents a comparison of voltage mode control (VMC) and two current mode control (CMC) methods of noninverting buck-boost converter. The converter control-to-output transfer function, line-to-output transfer function and the output impedance ...
M. Č. Bošković
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

3-D-Printed Two-Dielectric Rectangular Waveguide TE₁₀–TE₂₀ Mode Converter

IEEE Access
In this work a novel TE10–TE20 mode converter for rectangular waveguide (RW) is presented. The proposed structure is conceived as a device that can be inserted in an empty straight section of a RW to yield the desired mode conversion.
German Torregrosa-Penalva, Benjamin Potelon, Paula Viudes-Perez, Hector Garcia-Martinez, Enrique Bronchalo, Ernesto Avila-Navarro, Cedric Quendo   +6 more
doaj   +1 more source

Meta-Optics-Empowered Switchable Integrated Mode Converter Based on the Adjoint Method. [PDF]

Nanomaterials (Basel), 2022
Ha Y, Guo Y, Pu M, Xu M, Li X, Ma X, Zou F, Luo X.   +7 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Sliding Mode Control of a Bidirectional Buck/Boost DC-DC Converter with Constant Switching Frequency

Iranian Journal of Electrical and Electronic Engineering, 2018
In this paper, sliding mode control (SMC) for a bidirectional buck/boost DC-DC converter (BDC) with constant frequency in continuous conduction mode (CCM) is discussed.
A. Safari, H. Ardi
doaj  

Correction to: An ultra-compact polarization-insensitive slot-strip mode converter. [PDF]

Front Optoelectron, 2022
Tao Z, Wang B, Bai B, Chen R, Shu H, Zhang X, Wang X.   +6 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

A Novel Transformerless DC–DC Converters With High Step-Up Voltage Gain And Low Voltage Stress On The Switch [PDF]

Journal of Intelligent Procedures in Electrical Technology, 2016
In this paper, a single switch transformerless high step up dc-dc converter with low voltage stress on the switch is proposed. In the proposed converter only one switch is used which makes the control scheme simple as well as reducing the switching power
hossein ajdarfaeghi, Mohammadreza Banaei
doaj