Results 181 to 190 of about 7,683,030 (332)
Carbon fiber reinforced composite material layup design optimization method and its application in automobile battery box. [PDF]
Lu D +6 more
europepmc +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Modal Analysis-Based Detection of Barely Visible Impact Damage in Carbon/Epoxy Overwraps of Type-IV Polymer-Lined Pressure Vessels. [PDF]
Bocian M +4 more
europepmc +1 more source
Amendment of Identified Mode Shape for Component Mode Synthesis
Shigeru MORITA, Shouhe KUMANO
openaire +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Patellar and Femoral Bone Morphology Is Associated With Overweight and Sports Participation in Young Adolescents. [PDF]
van Paassen R +8 more
europepmc +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Neural Network-Enabled Process Flowsheet for Industrial Shot Peening. [PDF]
Feltner L, Mort P.
europepmc +1 more source
Second-harmonic generation in single-mode integrated waveguides based on mode-shape modulation
A. Rao +6 more
semanticscholar +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

