CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The importance of layer-dependent molecular twisting for the structural anisotropy of interfacial water. [PDF]
Fellows AP +5 more
europepmc +1 more source
Amendment of Identified Mode Shape for Component Mode Synthesis
Shigeru MORITA, Shouhe KUMANO
openaire +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Mode conversion of hyperbolic phonon polaritons in van der Waals terraces. [PDF]
Noh BI +9 more
europepmc +1 more source
Mode partition noise mitigation for VCSEL-MMF links by using wavefront shaping technique
Chenyu Liang +3 more
openalex +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Crashworthiness Analysis of Bio-Inspired Multi-Cell Concave Tubes. [PDF]
Deng X, Huang J, Xie J.
europepmc +1 more source
Theoretical framework for chip-scale wavefront shaping with transverse spatial mode modulation
Daniel M. Harrington +3 more
openalex +1 more source
Cloaking design for arbitrarily shape objects based on characteristic mode method
Yan Shi, Lin Zhang
openalex +1 more source

