Results 81 to 90 of about 131,690 (264)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Vietnam Journal of Mechanics, 2013 This article presents some results on the determination of the vibration shape function of a multiple cracked elastic beam element, which is modeled as an assembly of intact sub-segments connected by massless rotational springs.
Tran Van Lien, Trinh Anh Hao
doaj +1 more source
Changes in Frequency and Mode Shapes Due to Damage in Steel-Concrete Composite Beam. [PDF]
Materials (Basel), 2021 Jarosińska M, Berczyński S.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Delivery Mode Shapes the Composition of the Lower Airways Microbiota in Newborns. [PDF]
Front Cell Infect Microbiol, 2021 Cardelli E +10 more
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Stiffness estimation for large–sized umbrella space reflector
MATEC Web of Conferences, 2016 This work describes stiffness estimation for new large-sized (with aperture more than 50 m) umbrella space reflector. Reflector stiffness is measured by natural frequencies.
Belkov Alexey +5 more
doaj +1 more source
Modes of Feeding in Aggregations of Barnacles and the Shape of Aggregations
The Biological Bulletin, 1991 The interactions between the form of a barnacle aggregation, its flow environment, and the feeding behavior of each individual was determined in unidirectional flows; both models of barnacle aggregations and live barnacles were used. Hill-shaped aggregations of model barnacles captured significantly more particles than flat aggregations.
Pullen, J, Labarbera, Michael C
openaire +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source