Results 91 to 100 of about 131,690 (264)

A Mode Shape Identification Method of Timber Pieces Based on Relative Rigid Displacement Decomposition

open access: yesBioResources
As a commonly used method in the field of structural dynamic characteristics, mode shape identification currently relies largely on animation demonstrations of finite element modal analysis. This method is highly susceptible to the observer’s perspective
Panxu Sun   +4 more
doaj  

FEA-Based Vibration Modal Analysis and CFD Assessment of Flow Patterns in a Concentric Double-Flange Butterfly Valve Across Multiple Opening Angles

open access: yesVibration
A concentric double-flange butterfly valve (DN-500, PN-10) was analyzed to examine its dynamic behavior and internal fluid flow across multiple opening angles.
Desejo Filipeson Sozinando   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Passive Seismic Surveys for a Simplified Experimental Dynamic Characterization of the Messina Bell Tower (Sicily, Italy)

open access: yesApplied Sciences
This study proposes a simplified approach for the experimental dynamic characterization of the historic Messina Bell Tower (northeastern Sicily) using passive seismic single-station surveys.
Sabrina Grassi   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Effects of Cable on the Dynamics of a Cantilever Beam with Tip Mass

open access: yesShock and Vibration, 2016
The dynamic effects of cable attachment on a cantilever beam with tip mass are investigated by an improved Chebyshev spectral element method. The cabled beam is modeled as a double-beam system connected by springs at several discrete locations.
Yi-Xin Huang, Hao Tian, Yang Zhao
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

On complex mode shapes and their identification

open access: yesJournal of Physics: Conference Series
Abstract In experimental modal analysis, proportional damping is a convenient simplification that allows practitioners to fit their data to a model. However, this simplification seriously reduces the number of free parameters for fitting, and some systems may be misrepresented by the assumption of proportional damping.
openaire   +2 more sources

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