Results 111 to 120 of about 2,771,949 (296)
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A concentric double-flange butterfly valve (DN-500, PN-10) was analyzed to examine its dynamic behavior and internal fluid flow across multiple opening angles.
Desejo Filipeson Sozinando +2 more
doaj +1 more source
Assessment of Internal Damage in Sandwich Structures by Post-Processing of Mode Shapes Using Curvelet Transform. [PDF]
Katunin A, Ručevskis S.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Imaging the mode shapes of microdrum resonators
A setup was built to measure the local frequency response of (graphene) microdrums in order to image mode shapes. To this end, a laser interferometer that measures the local deflection of a microdrum was equipped with a very precisely movable sample ...
Slim, J.J. (author)
core
Modeshapes recognition using Fourier descriptors: a simple SHM example [PDF]
The main objective of this study is to develop an alternative criterion for modeshape classification, as the currently available one, MAC (Modal Assurance Criteria), is only a vector correlation representing modeshape similarities.
Morlier, Joseph +2 more
core
This study proposes a simplified approach for the experimental dynamic characterization of the historic Messina Bell Tower (northeastern Sicily) using passive seismic single-station surveys.
Sabrina Grassi +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Classifying Turbomachinery Blade Mode Shapes Using Artificial Neural Networks [PDF]
Currently, extensive signal analysis is performed in order to evaluate structural health of turbomachinery blades. This approach is affected by constraints of time and the availability of qualified personnel.
Ahmad Mehrabi, Hamid +2 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

