Results 41 to 50 of about 3,497,010 (299)

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig   +13 more
wiley   +1 more source

Bibliometric analysis of model-based systems engineering in advanced manufacturing [PDF]

open access: yesJournal of Intelligent Manufacturing and Special Equipment
Purpose – Model-based systems engineering (MBSE) is an important approach for the transforming process from “document-centered” to “model centered” systems engineering mode in equipment development, which can effectively shorten the equipment development
Jinzhi Lu   +3 more
doaj   +1 more source

Quantitative Set-Based Design to Inform Design Teams

open access: yesApplied Sciences, 2021
System designers, analysts, and engineers use various techniques to develop complex systems. A traditional design approach, point-based design (PBD), uses system decomposition and modeling, simulation, optimization, and analysis to find and compare ...
Eric Specking   +3 more
doaj   +1 more source

Model based system engineering approach of a lightweight embedded TCP/IP

open access: yes, 2011
The use of embedded software is growing very rapidly. Accessing the internet is a necessary service which has large range of applications in many fields. The Internet is based on TCP/IP which is a very important stack.
Hassan, Ahmed E.   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Applying Model-Based Systems Engineering to Tailings Storage Facility Structures

open access: yesMaterials Proceedings, 2023
Model-based systems engineering (MBSE) is a methodology that focuses on creating and exploiting the digital system and engineering domain models as the primary means of exchange of information, feedback, and requirements, as opposed to document-centric ...
Bartłomiej Bursa   +2 more
doaj   +1 more source

A Practical Environment to Apply Model-Driven Web Engineering [PDF]

open access: yes, 2009
The application of a model-driven paradigm in the development of Web Systems has yielded very good research results. Several research groups are defining metamodels, transformations, and tools which offer a suitable environment, known as model-driven ...
Escalona Cuaresma, María José   +7 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Quality-aware model-driven service engineering [PDF]

open access: yes, 2008
Service engineering and service-oriented architecture as an integration and platform technology is a recent approach to software systems integration.
Barrett, Ronan   +3 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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