Results 71 to 80 of about 11,397 (304)

Flexible Implantable Silicon Carbide Multi‐Electrode Array (MEA) for Cell Multichannel Recording and Cell Ablation

open access: yesAdvanced Materials Technologies, EarlyView.
Flexible silicon carbide (SiC) microelectrode arrays enable high‐fidelity, multichannel cell extracellular recording and precise localized ablation. SiC has been extensively evaluated to persist long‐term in chronic physiological conditions while remaining robust, with excellent electrical and electrochemical stability.
Minh Anh Huynh   +4 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

open access: yesAdvanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis   +7 more
wiley   +1 more source

Modelinės architektūros naudojimas kuriant komponentines programų sistemas

open access: yesInformacijos Mokslai, 2009
Modelinė architektūra gana paplitusi, tačiau jos taikymai komponentinei paradigmai yra tik daliniai – neatsižvelgiama į reikalavimą atskirti komponentų ir komponentinių sistemų kūrimo procesus.
Vaidas Giedrimas
doaj   +1 more source

Towards Agent-oriented Model-Driven Architecture [PDF]

open access: yes, 2007
Model Driven Architecture supports the transformation from reusable models to executable software. Business representations, however, cannot be fully and explicitly represented in such models for direct transformation into running systems.
Xiao, Liang, Greer, Des
core  

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

open access: yesAdvanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel   +16 more
wiley   +1 more source

Pattern-Based Coarse-Grained Component Modelling for Enterprise Application Software Developing

open access: yesMATEC Web of Conferences, 2016
To improve the efficiency of ESA (Enterprise Application Software) development, component-based software development is a good solution. However, though those general software components, like JavaBean, COM/COM+ (Component Object Model), are maturely ...
Li Hai Bo, Liang Meng Xia, Gao Ya Feng
doaj   +1 more source

Software representation methodology for agile application development: An architectural approach

open access: yesRedes de Ingeniería, 2016
The generation of Web applications represents the execution of repetitive tasks, this process involves determining information structures, the generation of different types of components and finally deployment tasks and tuning applications.
Alejandro Paolo Daza Corredor   +2 more
doaj   +1 more source

Distribution pattern-driven development of service architectures [PDF]

open access: yes, 2009
Distributed systems are being constructed by composing a number of discrete components. This practice is particularly prevalent within the Web service domain in the form of service process orchestration and choreography.
Barrett,Ronan   +3 more
core   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo   +14 more
wiley   +1 more source

A Model Driven Framework for Collaborative and Dynamic Design and Implementation of NoSQL-Oriented Data warehouses

open access: yesJordanian Journal of Computers and Information Technology
Nowadays, modernizing the data warehouse ecosystem is a key challenge in decision support systems. This modernization is crucial for ensuring scalability and meeting evolving business requirements, especially with the advent of big data.
Khadija Letrache, Mohammed Ramdani
doaj   +1 more source

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