Results 71 to 80 of about 4,928,263 (304)

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

open access: yes
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari   +9 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Model-based approach for specifying requirements of virtual reality software products

open access: yesFrontiers in Virtual Reality
IntroductionGathering requirements for developing virtual reality (VR) software products is a labor-intensive process. It requires detailed elicitation of scene flow, articles in the scene, action responses, custom behaviors, and timeline of events.
Sai Anirudh Karre, Y. Raghu Reddy
doaj   +1 more source

Model-Driven Development

open access: yes, 2009
The purpose of this publication is to describe the state-of-the-art and results of two surveys about the model-driven development (MDD), particularly from the processes viewpoint. The study and surveys were carried out in the "Model-driven development of highly configurable embedded Software-intensive Systems (MoSiS)" ITEA project.
Takalo Juha   +3 more
openaire   +1 more source

Development of service-oriented architectures using model-driven development: A mapping study

open access: yesInformation and Software Technology, 2015
ContextModel-Driven Development (MDD) and Service-Oriented Architecture (SOA) are two challenging research areas in software engineering. MDD is about improving software development whilst SOA is a service-based conceptual development style, therefore ...
David Ameller   +5 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Novel Reference Method for the Characterization of PD Measuring Systems Using HFCT Sensors

open access: yesSensors
During their lifespan, high-voltage (HV) electrical systems are subjected to operating conditions in which electrical, mechanical, thermal and environmental-related stresses occur.
Eduardo Arcones   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Implementation-driven of Development Planning Model [PDF]

open access: yesمدیریت دولتی
ObjectiveDespite Iran’s long history of national development planning and the considerable investment of human and financial resources, the country has not successfully realized the goals outlined in its plans.
Reza Vaezi   +3 more
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

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