Results 91 to 100 of about 1,736,997 (282)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Rapid Prototyping of Multi-Functional Battery Energy Storage System Applications
Applied Sciences, 2018 Battery Energy Storage Systems (BESS) are starting to play an important role in today’s power distribution networks. They provide a manifold of services for fulfilling demands and requests from diverse stakeholders, such as distribution system operators,
Claudia Zanabria +3 more
doaj +1 more source
Formality, Evolution, and Model-driven Software Engineering
Electronic Notes in Theoretical Computer Science, 2005 AbstractThis paper introduces an approach to software development in which a series of working implemen- tations are generated automatically from a series of formal specifications. The implementations are data stores, communicating through standard protocols.
Davies, J +4 more
openaire +3 more sources
Combining Model-Driven Engineering and Cloud Computing [PDF]
, 2010 Service-orientation and model-driven engineering are two of the most dominant software engineering paradigms nowadays. This position paper explores the synergies between them and show how they can benefit from each other.
Bruneliere, Hugo +2 more
core +1 more source
, 2014 Designing complex engineering systems, such as an aircraft or an aero-engine, is immensely challenging. Formal Systems Engineering (SE) practices are widely used in the aerospace industry throughout the overall design process to minimise the overall ...
Bertoni, M. +3 more
core +3 more sources
An ontology framework for developing platform-independent knowledge-based engineering systems in the aerospace industry [PDF]
, 2014 This paper presents the development of a novel knowledge-based engineering (KBE) framework for implementing platform-independent knowledge-enabled product design systems within the aerospace industry.
Sanya, I. O., Shehab, Essam
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Towards Guidelines for Preventing Critical Requirements Engineering Problems [PDF]
, 2016 Context] Problems in Requirements Engineering (RE) can lead to serious consequences during the software development lifecycle. [Goal] The goal of this paper is to propose empirically-based guidelines that can be used by different types of organisations ...
Felderer, M. +4 more
core +2 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A quality management based on the Quality Model life cycle [PDF]
, 2012 Managing quality is a hard and expensive task that involves the execution and control of processes and techniques. For a good quality management, it is important to know the current state and the objective to be achieved.
Domínguez Mayo, Francisco José +4 more
core +1 more source