Results 61 to 70 of about 2,892,641 (307)
Data-driven causal analysis of observational biological time series
eLife, 2022 Complex systems are challenging to understand, especially when they defy manipulative experiments for practical or ethical reasons. Several fields have developed parallel approaches to infer causal relations from observational time series.
Alex Eric Yuan, Wenying Shou
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
CoRRIn general reinforcement learning, all established optimal agents, including AIXI, are model-based, explicitly maintaining and using environment models. This paper introduces Universal AI with Q-Induction (AIQI), the first model-free agent proven to be asymptotically $\varepsilon$-optimal in general RL.
Yegon Kim, Juho Lee
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
IEEE AccessMost reinforcement learning (RL) algorithms proposed to solve Nash equilibrium in multi-agent systems assume stable communication conditions or rely on accurate models of the environment.
Yuannan Jiang +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
IEEE Access, 2018 To ensure high control performance of cable-driven robots under complicated lumped uncertainties, we propose a novel time-delay control (TDC) scheme with adaptive fractional-order nonsingular terminal sliding mode (AFONTSM) in this paper.
Yaoyao Wang +4 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Enhanced Secure Transmission Against Intelligent Attacks
IEEE Access, 2019 In this paper, we proposed an enhanced secure scheme for the wireless communication system threatened by an intelligent attacker, which can work in eavesdropping, jamming, and spoofing modes.
Chao Li +4 more
doaj +1 more source
Matrix Completion with Model-free Weighting
CoRR, 2021 Proceedings of the 38th International Conference on Machine Learning, PMLR 139 ...
Jiayi Wang +3 more
openaire +3 more sources