Comprehensive profiling of cell-free RNA in seminal plasma reveals functional links to spermatogenic impairment. [PDF]
Zhou Q +15 more
europepmc +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Discovery and validation of a multi-protein panel for predicting non-fatal major adverse cardiovascular events in diabetic kidney disease. [PDF]
Jiang L +5 more
europepmc +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Prognostic value of melatonin-related signature genes in lung adenocarcinoma. [PDF]
Guo H, Liu L, Lu Y, Ma Y, Ren X, Cui T.
europepmc +1 more source
Primary healthcare professionals' perspectives on mobility limitation assessment and predictive model optimization for community-dwelling older adults: a qualitative research. [PDF]
Chen L +5 more
europepmc +1 more source
Artificial intelligence in ovarian cancer prevention and control: a brief review of detection, treatment, and equity (2021-2026). [PDF]
Huang Z, Wei B, Shen Y.
europepmc +1 more source
Combining PSA density and imaging data with transcript markers from urinary cells to improve prediction of prostate cancer reclassification in patients on active surveillance. [PDF]
Borkowetz A +5 more
europepmc +1 more source
METLUNG: plasma metabolomic profiling identifies metabolomic signatures associated with immunotherapy outcomes in non-small cell lung cancer. [PDF]
Lucía-Gozálvez C +9 more
europepmc +1 more source

