Results 51 to 60 of about 914,662 (294)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Multi-level quantum Diesel engine of non-interacting fermions in a one-dimensional box

open access: yes, 2020
We consider the toy model of quantum Diesel cycle without temperature constructed from non-interacting fermions, which are trapped in a one-dimensional box.
Ram, Shish, Singh, Satnam
core   +1 more source

Better text compression from fewer lexical n-grams [PDF]

open access: yes, 2001
Word-based context models for text compression have the capacity to outperform more simple character-based models, but are generally unattractive because of inherent problems with exponential model growth and corresponding data sparseness.
Lorenz, Michelle, Smith, Tony C.
core   +2 more sources

Differentially Private Model Compression

open access: yes, 2022
Recent papers have shown that large pre-trained language models (LLMs) such as BERT, GPT-2 can be fine-tuned on private data to achieve performance comparable to non-private models for many downstream Natural Language Processing (NLP) tasks while simultaneously guaranteeing differential privacy.
Mireshghallah, Fatemehsadat   +4 more
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Boosting Lightweight CNNs Through Network Pruning and Knowledge Distillation for SAR Target Recognition

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021
Deep convolutional neural networks (CNNs) have yielded unusually brilliant results in synthetic aperture radar (SAR) target recognition. However, overparameterization is a widely-recognized property of deep CNNs, and most previous works excessively ...
Zhen Wang, Lan Du, Yi Li
doaj   +1 more source

Semilogarithmic Nonuniform Vector Quantization of Two-Dimensional Laplacean Source for Small Variance Dynamics [PDF]

open access: yes, 2012
In this paper high dynamic range nonuniform two-dimensional vector quantization model for Laplacean source was provided. Semilogarithmic A-law compression characteristic was used as radial scalar compression characteristic of two-dimensional vector ...
Panic, S., Peric, Z., Savic, M.
core   +1 more source

Failure analysis of CFRP laminates subjected to Compression After Impact: FE simulation using discrete interface elements [PDF]

open access: yes, 2013
This paper presents a model for the numerical simulation of impact damage, permanent indentation and compression after impact (CAI) in CFRP laminates.
Bouvet, Christophe   +2 more
core   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Optimized AlexNet Pruning for Edge-Based Medical Diagnostics

open access: yesIEEE Access
Medical diagnostics demand rapid and accurate disease detection to ensure timely treatment, directly impacting human lives. Deep neural networks (DNNs) have shown unparalleled success in medical applications, surpassing traditional methods.
Yasser A. Amer   +2 more
doaj   +1 more source

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