Results 71 to 80 of about 293,454 (315)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Ductilityof fiber-reinforcedself-consolidatingconcreteundermulti-axial compression [PDF]
, 2011 The results of 12 multi-axial compression tests performed on cylinders made of self-consolidating concrete, plain (SCC) and reinforced with steel fibers (FR-SCC), are presented.
Paolo Vallini +5 more
core +1 more source
Compressing the inert doublet model [PDF]
Physical Review D, 2016 The Inert Doublet Model relies on a discrete symmetry to prevent couplings of the new scalars to Standard Model fermions. This stabilizes the lightest inert state, which can then contribute to the observed dark matter density. In the presence of additional approximate symmetries, the resulting spectrum of exotic scalars can be compressed.
Blinov, Nikita +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Visual saliency from image features with application to compression
, 2012 Image feature point algorithms and their associated regional de-scriptors can be viewed as primitive detectors of visually-salient information.In this paper, a new method for constructing a visual attention probabilitymap using features is proposed ...
Robertson, Neil, Harding, P. J.
core +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Findings of the Association for Computational Linguistics: EMNLP 2024Large language models (LLMs) exhibit excellent performance in various tasks. However, the memory requirements of LLMs present a great challenge when deploying on memory-limited devices, even for quantized LLMs. This paper introduces a framework to compress LLM after quantization further, achieving about 2.2x compression ratio.
Weilan Wang +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 2007 3D imaging techniques have the potential to establish a future mass-market in the fields of entertainment and communications. Integral imaging, which can capture true 3D color images with only one camera, has been seen as the right technology to offer ...
Adedoyin, S +5 more
core +1 more source