Results 191 to 200 of about 11,068 (304)

A 3D Collagen-Based In Vitro Cancer Model Created Through Modular Tissue Engineering. [PDF]

Cancers (Basel)
Daneshvar Baghbadorani N, Bosso M, Greene R, Dzikowski T, Bevelander B, Gagnon A, Johannson M, Javan M, Soori P, Chamberlain MD.   +9 more
europepmc   +1 more source

Clinical manifestations of dual‐gene variants in retinitis pigmentosa

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram, Jan‐Philipp Bodenbender, David A. Merle, Milda Reith, Anton Sonntag, Krunoslav Stingl, Tobias B. Haack, Theresia Zuleger, Bernd Wissinger, Laura Kühlewein, Katarina Stingl, Susanne Kohl   +11 more
wiley   +1 more source

Scaffold-free 3D-cell co-culture model system for the study of metastatic cancer in the brain TME. [PDF]

PLoS One
Sarkar P, Ahuja S, Lazar IM.
europepmc   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source

Strengthening health systems through NTD integration: Key insights from a multi-country webinar. [PDF]

PLoS Negl Trop Dis
Rozendaal N, Bassabi-Alladji MA, Bishaw T, Omondi W, Tolotra AF, Batchiri SA, Nshimiyimana L, Gnossike P, Jones C, Mubangizi A, Rebollo M.   +10 more
europepmc   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

BioGate SERS Chip enables robust metabolite-oriented nanobiotechnological detection of breast cancer margins. [PDF]

J Nanobiotechnology
Huang G, Hao S, Fang Y, Pei J, Wang Y, Shao J, Bao L, Li Z, Cao W, Zhao M, Hou L, Wang H.   +11 more
europepmc   +1 more source

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

Cell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia, Man Li, Yanyu Chen, Jialin Chen, Yuting Cui, Xi‐Long Zheng, Jing Yang, Bingzhao Li, Xiaofeng Ma, Miao Liu, Gang Fan, Juan Peng, Xiaoyan Dai, Zhihan Tang   +13 more
wiley   +1 more source

Model-Driven Engineering : Application oh the IEEE 15288 standard, of the MDA architecture and the SysML language to mechatronics systems design

, 2008
Mechatronics systems design, because of their complexity, necessitates systemic approach. A systemic approach means the use of a methodology that allows to consider the whole system with all its components (mechanical, electronical, software, etc.), and to offer the possibility to design and specify the system by the definition of its components and ...
openaire   +1 more source

Obesity, Inflammation, and Tumor Microenvironment in Three-Dimensional Models of Breast Cancer. [PDF]

Cells
Salinas-Vera YM, Pérez-Navarro Y, Puente-Rivera J, Álvarez-Sánchez ME, López-Camarillo C.   +4 more
europepmc   +1 more source