Results 201 to 210 of about 9,597 (251)

An agile approach on model-driven architecture (MDA)

, 2005
openaire   +1 more source

Apigenin attenuates obesity-associated hepatic dysfunction and fibrosis in rats: an integrated biochemical, histological, and ex vivo dielectric study. [PDF]

BMC Pharmacol Toxicol
Moussa SA, Aziz S, Abdel-Rahman RF, Elbaset MA, Fayed HM, Shabana ME, Ibrahim FA, Bashandy SAE.   +7 more
europepmc   +1 more source

Multi‐gradient warming reshapes functional traits and adaptive responses of alpine meadow plants

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant functional traits in alpine meadows are critical indicators of ecosystem responses to climate warming, yet dynamic changes in trait networks across warming gradients and their consequences for community functions remain poorly understood.
Zhiwei Yan, Feipeng Ren, Haocun Zhao, Baoyang Sun, Hao Li, Jinquan Huang, Jigen Liu   +6 more
wiley   +1 more source

A Natural Monoterpene, Carvacrol, Mitigates Bisphenol A-Triggered Hepatorenal Oxidative Damage, Pro-Inflammatory Gene Expression, and Histopathological Alterations in Rats. [PDF]

Life (Basel)
Küçükbüğrü N, Acaroz U.
europepmc   +1 more source

Comparative Genomics and Functional Evidence for Convergent Adaptation to Hypoxia in Mammals

Integrative Zoology, EarlyView.
This study reveals convergent selection in mammals adapted to hypoxia. Functional assays demonstrate that amino acid mutations reduce oxidative stress, attenuate hypoxia‐induced injury, and modulate the hypoxia‐inducible transcription factor (HIF)‐driven hypoxic response.
Hao Dong, Chunxu Wang, Enqing Pei, Liang Zhao, Simin Chai, Ran Tian   +5 more
wiley   +1 more source

Polyploid Giant Cancer Cells as a Senescence-Linked State in the Tumor Microenvironment. [PDF]

Cancers (Basel)
Dawson MR, Ghosh D.
europepmc   +1 more source

Clinical manifestations of dual‐gene variants in retinitis pigmentosa

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram, Jan‐Philipp Bodenbender, David A. Merle, Milda Reith, Anton Sonntag, Krunoslav Stingl, Tobias B. Haack, Theresia Zuleger, Bernd Wissinger, Laura Kühlewein, Katarina Stingl, Susanne Kohl   +11 more
wiley   +1 more source

A scalable reinforcement learning approach for screening large peptide libraries for bioactive peptide discovery. [PDF]

Nat Commun
Pandey M, Foo J, Massah S, Alford MA, Mslati H, Subbaraj G, Saba M, Gentile F, Lallous N, Haney EF, Hancock REW, Ester M, Cherkasov A.   +12 more
europepmc   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

A lightweight hybrid transformer approach for hyperspectral imaging-based drought tolerance evaluation in tea plants. [PDF]

Plant Methods
Li Y, Zhang Y, Wang Y, Chen H, Han X, Mao Y, Sun L, Shen J, Ding Z.   +8 more
europepmc   +1 more source