Results 71 to 80 of about 1,785,688 (300)
Machines, 2023 Software development for robotic systems is traditionally performed based on simulations, manual code implementation, and testing. However, this software development approach can cause safety issues in some scenarios, including multiple robots sharing a ...
Metin Ozkan +3 more
doaj +1 more source
Model Driven Interoperability for System Engineering
Modelling, 2020 To keep up to date, manufacturing enterprises need to use the latest results from the ICT sector, especially when collaborating with external partners in a supply chain and exchanging products and data.
G. Zacharewicz +3 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Quality-Driven Detection and Resolution of Metamodel Smells
IEEE Access, 2019 In model-driven engineering, analogously to any software development practice, metamodel design must be accurate and performed by considering relevant quality factors, including maintainability, reusability, and understandability.
Lorenzo Bettini +3 more
doaj +1 more source
Semantic model driven engineering
, 2020 Semantic interoperability is a concern in the design and implementation of modern information systems. Whenever two systems communicate it is important that they share an adequate, common interpretation of any information transferred. Similarly, whenever data created or ac- quired in one context is used in another, it is important that the provenance ...
openaire +3 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A survey on modeling and model-driven engineering practices in the embedded software industry
Journal of systems architecture, 2018 Software-intensive embedded systems have become an essential aspect of our lives. To cope with its growing complexity, modeling and model-driven engineering (MDE) are widely used for analysis, design, implementation, and testing of these systems. Since a
Deniz Akdur, V. Garousi, Onur Demirörs
semanticscholar +1 more source
Towards Human-centric Model-driven Software Engineering
International Conference on Evaluation of Novel Approaches to Software Engineering, 2020 : Many current software systems suffer from a lack of consideration of the human differences between end users. This includes age, gender, language, culture, emotions, personality, education, physical and mental challenges, and so on.
J. Grundy +2 more
semanticscholar +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source