Results 71 to 80 of about 1,764,274 (298)

Quality-Driven Detection and Resolution of Metamodel Smells

open access: yesIEEE Access, 2019
In model-driven engineering, analogously to any software development practice, metamodel design must be accurate and performed by considering relevant quality factors, including maintainability, reusability, and understandability.
Lorenzo Bettini   +3 more
doaj   +1 more source

Safety Verification of Multiple Industrial Robot Manipulators with Path Conflicts Using Model Checking

open access: yesMachines, 2023
Software development for robotic systems is traditionally performed based on simulations, manual code implementation, and testing. However, this software development approach can cause safety issues in some scenarios, including multiple robots sharing a ...
Metin Ozkan   +3 more
doaj   +1 more source

Feasibility of EPC to BPEL Model Transformations Based on Ontology and Patterns [PDF]

open access: yes, 2010
Model-Driven Engineering holds the promise of transforming\ud business models into code automatically. This requires the concept of\ud model transformation.
Eckartz, Silja M.   +2 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Computer-aided design for building multipurpose routing processes in discrete event simulation models

open access: yesEngineering Science and Technology, an International Journal, 2021
Good domain-modeling enables an appropriate separation of concerns that improves quality properties in the simulation models, such as modifiability and maintainability.
María Julia Blas, Silvio Gonnet
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An Experiment in Model Driven Architecture for e-Enterprise Systems [PDF]

open access: yes, 2002
OMG's Model Driven Architecture demonstrates how a system's specification model can be used within the process of creating supporting software implementations.
Kent, Stuart, Smith, Robert P.
core  

Semantic model driven engineering

open access: yes, 2020
Semantic interoperability is a concern in the design and implementation of modern information systems. Whenever two systems communicate it is important that they share an adequate, common interpretation of any information transferred. Similarly, whenever data created or ac- quired in one context is used in another, it is important that the provenance ...
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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