Model-Driven Approaches for Reverse Engineering—A Systematic Literature Review
IEEE AccessMany organizations depend on software systems to accomplish their daily tasks, but these systems need to be maintained and evolved to cope with various changes and requirements.
Hanan Abdulwahab Siala +2 more
doaj +1 more source
Dirty engineering data-driven inverse prediction machine learning model
Scientific Reports, 2020 Most data-driven machine learning (ML) approaches established in metallurgy research fields are focused on a build-up of reliable quantitative models that predict a material property from a given set of material conditions.
Jin-Woong Lee +5 more
doaj +1 more source
A methodological proposal and tool support for the HL7 standards compliance in the development of health information systems [PDF]
, 2017 Health information systems are increasingly complex, and their development is presented as a challenge for software development companies offering quality, maintainable and interoperable products.
Domínguez-Mayo, F.J +7 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A brief introduction to model-driven engineering
Tecnura, 2014 La crisis del software es un concepto que comenzó a utilizarse en 1968, en la primera conferencia organizada por la Organización del Tratado del Atlántico Norte (OTAN) en el desarrollo de software.
Vicente García Díaz +5 more
doaj
An Integrated Modeling, Simulation and Analysis Framework for Engineering Complex Systems
IEEE Access, 2019 The discipline of component-based modeling and simulation offers promising gains in reducing cost, time, and the complexity of model development through the (re)use of modular components.
Imran Mahmood +4 more
doaj +1 more source
Model Driven Language Engineering
Electronic Notes in Theoretical Computer Science, 2003 AbstractThere is currently much interest in model driven approaches to software engineering. The basic idea is to make business, architecture and design models frst class artefacts that are not discarded once the code gets built, but rather can be exercised independently, be reconciled with each other and underlying implementations, and used to ...
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Towards Guidelines for Preventing Critical Requirements Engineering Problems [PDF]
, 2016 Context] Problems in Requirements Engineering (RE) can lead to serious consequences during the software development lifecycle. [Goal] The goal of this paper is to propose empirically-based guidelines that can be used by different types of organisations ...
Felderer, M. +4 more
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source