Results 61 to 70 of about 308,743 (257)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
World Electric Vehicle JournalIn order to solve the problems of thermal management efficiency and temperature control accuracy in the passenger compartment of electric vehicles, the phase change thermal storage design concept and the model-free adaptive control method are applied to ...
Zhiqiang Zhu, Wenchen Xie, Xianfeng Du
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Ultra-Local Model-Based Adaptive Enhanced Model-Free Control for PMSM Speed Regulation
MachinesConventional model-free control (MFC) is widely used in motor drives due to its simplicity and model independence, yet its performance suffers from imperfect disturbance estimation and input gain mismatch.
Chunlei Hua +3 more
doaj +1 more source
An improved compact-form antisaturation model-free adaptive control algorithm for a class of nonlinear systems with time delays. [PDF]
Sci Prog, 2023 Wu L, Li Z, Liu S, Li Z, Sun D.
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Model-Free Adaptive Model Predictive Control for Trajectory Tracking of Autonomous Mining Trucks
SensorsThe trajectory-tracking capability of autonomous mining trucks is critical for accomplishing transportation tasks efficiently. However, due to the diverse road surfaces and rugged terrains in open-pit mines, the existing vehicle dynamics models struggle ...
Feixiang Xu +3 more
doaj +1 more source
Model-Free Adaptive Predictive Control for an Urban Road Traffic Network via Perimeter Control
IEEE Access, 2019 This paper proposes a novel model-free adaptive control (MFAC) strategy for urban road traffic network via perimeter control based on dynamic linearization technique and predictive control.
Zhenxuan Li +3 more
doaj +1 more source