Results 111 to 120 of about 13,855,951 (296)

Detecting model misspecification in cosmology with scale-dependent normalizing flows

open access: yesMachine Learning: Science and Technology
Current and upcoming cosmological surveys will produce unprecedented amounts of high-dimensional data, which require complex high-fidelity forward simulations to accurately model both physical processes and systematic effects which describe the data ...
Aizhan Akhmetzhanova   +2 more
doaj   +1 more source

Parameter misspecification and robust monetary policy rules [PDF]

open access: yes
In this paper, I evaluate the performance deterioration that occurs when the central bank employs an optimal targeting rule that is based on incorrect parameter values.
Walsh, Carl E.
core  

Acknowledging Misspecification in Macroeconomic Theory

open access: yes, 2002
We explore methods for confronting model misspecification in macroeconomics. We construct dynamic equilibria in which private agents and policy makers recognize that models are approximations.
Thomas J. Sargent, Lars Peter Hansen
core   +1 more source

Population Pharmacokinetics and Exposure‐Response Analyses to Support Cofetuzumab Pelidotin (ABBV‐647) Dose Optimization in Non‐Small Cell Lung Cancer Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cofetuzumab pelidotin (Cofe‐P) is an anti‐protein tyrosine kinase 7 (PTK7) antibody‐drug conjugate (ADC) being investigated for the treatment of adults with PTK7‐expressing, recurrent non‐small cell lung cancer (NSCLC). The first‐in‐human (FIH) trial demonstrated tolerability of dosages ≤ 2.8 mg/kg once every 3 weeks (Q3W) and ≤ 3.2 mg/kg Q2W ...
Carla Biesdorf   +8 more
wiley   +1 more source

Assessing Goodness-of-Fit Tests Based on Pairwise Concordant Marginal Information for Generalized Linear Mixed Models Under Second-Order Serial Error Dependence

open access: yesMathematics
Traditional goodness-of-fit tests for binary longitudinal data can perform poorly when response-pattern tables are sparse. Concordant information-based tests mitigate this issue by using lower-dimensional marginal information, but their performance under
Jinhui Xu   +4 more
doaj   +1 more source

Sequential design augmentation with model misspecification

open access: yes, 2007
In Response Surface Methodology (RSM) one attempts to model some variable of interest, usually as a known function of design variables. Subsequent analysis often indicates a need to move to a new region of interest.
Sutherland, Sindee S.
core  

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Contemporary challenges in model misspecification

open access: yes
2024In contemporary practical applications, the significance of model misspecification has grown notably in many fields. When statistical inferences are based on likelihoods, model misspecification can give rise to inaccurate uncertainty quantification ...
Li, Jiawei
core   +1 more source

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