Results 121 to 130 of about 13,855,951 (296)

From Biological Mechanisms to Causal Inference: Quantitative Systems Pharmacology and Causal Frameworks in Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Digital patients and in silico clinical trials offer new opportunities to advance pharmacological research, clinical development, and regulatory decision‐making by enabling the simulation of treatment effects prior to testing in patients. Among the most promising of these opportunities is the combined use of quantitative systems pharmacology (QSP) and ...
Thomas Klabunde   +3 more
wiley   +1 more source

MULTIPARAMETRIC AND HIERARCHICAL SPATIAL AUTOREGRESSIVE MODELS: THE EVALUATION OF THE MISSPECIFICATION OF SPATIAL EFFECTS USING A MONTE CARLO SIMULATION

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2014
The aim of this paper is to evaluate the spatial and hierarchical models for data generating processes with spatial heterogeneity and spatial dependence at the higher level.
Edyta Łaszkiewicz
doaj  

Orchestrating Green Transformation: How AI Adoption Enables Corporate Carbon Neutrality

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT As carbon neutrality has become a central goal of global climate governance, how firms achieve low‐carbon transformation has emerged as a critical research issue. However, prior studies have primarily focused on macro‐ or industry‐level analyses, offering limited and fragmented insights into how digital technologies—particularly AI—affect firm‐
Xiaonan Dong, Sungjin Son
wiley   +1 more source

A comparison of covariate adjustment approaches under model misspecification in individually randomized trials. [PDF]

open access: yesTrials, 2023
Tackney MS   +5 more
europepmc   +1 more source

Imputation Estimators Partially Correct for Model Misspecification

open access: yes, 2011
Inference problems with incomplete observations often aim at estimating population prop-erties of unobserved quantities. One simple way to accomplish this estimation is to impute the unobserved quantities of interest at the individual level and then take
Vladimir N. Minin   +3 more
core   +1 more source

Family Control and Ownership, Corporate Culture, and ESG Performance in Thailand

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Motivated by the growing importance of environmental, social, and governance (ESG) performance in emerging markets, we examine how family control and ownership, together with corporate culture, influence the ESG performance of publicly listed firms in Thailand.
Sirimon Treepongkaruna   +2 more
wiley   +1 more source

Modelling the Incremental Value of Personality Facets: The Domains‐Incremental Facets‐Acquiescence Bifactor Model

open access: yesEuropean Journal of Personality, EarlyView., 2020
Abstract Personality can be described at different levels of abstraction. Whereas the Big Five domains are the dominant level of analysis, several researchers have called for more fine‐grained approaches, such as facet‐level analysis. Personality facets allow more comprehensive descriptions, more accurate predictions of outcomes, and a better ...
Daniel Danner   +4 more
wiley   +1 more source

Estimation and Model Misspecification for Recurrent Event Data with Covariates Under Measurement Errors

open access: yesMathematics
For subject i, we monitor an event that can occur multiple times over a random observation window [0, τi). At each recurrence, p concomitant variables, xi, associated to the event recurrence are recorded—a subset (q≤p) of which is measured with errors ...
Ravinath Alahakoon   +3 more
doaj   +1 more source

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