Results 31 to 40 of about 957,044 (346)
A Multilevel Study of Eupatorin and Scutellarein as Anti-Amyloid Agents in Alzheimer’s Disease
Today, Alzheimer’s disease (AD)—the most common neurodegenerative disorder, which affects 50 million people—remains incurable. Several studies suggest that one of the main pathological hallmarks of AD is the accumulation of abnormal amyloid beta (Aβ ...
Aikaterini E. I. Rizou+10 more
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Yeasts are eukaryotic heterotrophic organisms belonging to fungi. In contrast to other eukaryotes yeasts possess thick and rigid cell wall. As a source of carbon and energy yeast can degrade sugars using two metabolic pathways: aerobic respiration and ...
Jana KOPECKÁ+2 more
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Hansenula polymorpha: An attractive model organism for molecular studies of peroxisome biogenesis and function [PDF]
In wild-type Hansenula polymorpha the proliferation of peroxisomes is induced by various unconventional carbon- and nitrogen sources. Highest induction levels, up to 80% of the cytoplasmic volume, are observed in cells grown in methanol-limited chemostat
Harder, W.,+3 more
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Isoprene oxidation by the gram-negative model bacterium variovorax sp. WS11 [PDF]
Plant-produced isoprene (2-methyl-1,3-butadiene) represents a significant portion of global volatile organic compound production, equaled only by methane.
Crombie, Andrew T.+4 more
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A hundred spotlights on microbiology: how microorganisms shape our lives
Viral, bacterial, fungal and protozoal biology is of cardi-nal importance for the evolutionary history of life, ecol-ogy, biotechnology and infectious diseases.
Didac Carmona-Gutierrez+7 more
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Yeast as a Model Organism [PDF]
Yeast have many genes with homologs in humans. Has our understanding of these genes helped our understanding of human biology or disease? In his Perspective, Botstein argues "yes" and, as an example, discusses a report in this week9s issue by Sinclair et al.
Steven A. Chervitz+2 more
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Uberon: towards a comprehensive multi-species anatomy ontology [PDF]
The lack of a single unified species-neutral ontology covering the anatomy of a variety of metazoans is a hindrance to translating model organism research to human health.
Chris Mungall+3 more
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Models of Organic Organization in Montpellier Vitalism [PDF]
The species of vitalism discussed here is a malleable construct, often with a poisonous reputation (but one which I want to rehabilitate), hovering in between the realms of the philosophy of biology, the history of medicine, and the scientific background of the Radical Enlightenment (case in point, the influence of vitalist medicine on Diderot).
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IntroductionThe new targeted gene editing technologies, such as the CRISPR/Cas system, enable researchers to insert or delete genes at targeted loci efficiently.
Yang Guo+7 more
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Lagomorpha as a Model Morphological System
Due to their global distribution, invasive history, and unique characteristics, European rabbits are recognizable almost anywhere on our planet. Although they are members of a much larger group of living and extinct mammals [Mammalia, Lagomorpha (rabbits,
Brian Kraatz+21 more
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