Results 121 to 130 of about 735,742 (300)
Beilstein Journal of Organic Chemistry, 2012 Mitochondria undergo dynamic fusion and fission events that affect the structure and function of these critical energy-producing cellular organelles.
Laurie F. Mottram +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Model Organisms: Living Laboratories
, 2014 27-30The use of model organisms in biological science has come a long way.
Sengupta, Saswati
core
Other model organisms for sarcomeric muscle diseases.
, 2008 International audienceModel organisms are vital to our understanding of human muscle biology and disease. The potential of the nematode Caenorhabditis elegans, the fruitfly, Drosophila melanogaster and the zebrafish, Danio rerio, as model genetic ...
John Sparrow +5 more
core +1 more source
Representing with model organisms: A refined DEKI account [PDF]
In this article, we mobilize and refine the DEKI account of scientific representation to show that model organisms are not models but model ‘carriers,’ only abstracted and selected ‘parts’ of which are included in biological models.
Fábregas-Tejeda, Alejandro +1 more
core +3 more sources
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Reproductive aging: insights from model organisms
, 2011 Aging was once thought to be the result of a general deterioration of tissues as opposed to their being under regulatory control. However, investigations in a number of model organisms have illustrated that aspects of aging are controlled by genetic ...
Needhi Bhalla, Alice L. Ye
core +1 more source