Results 111 to 120 of about 735,742 (300)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Implementation of the precautionary approach in the regulation of genetically modified organisms: an African context

, 2011
Includes abstract.Includes bibliographical references.This thesis critically examines the regulation of genetically modified organisms (GMOs) in the selected countries of South Africa, Kenya, Zambia and Namibia.
Moitui, Charles Otuke
core  

Bridging the gap from ocean models to population dynamics of large marine predators: A model of mid-trophic functional groups [PDF]

, 2009
The modeling of mid-trophic organisms of the pelagic ecosystem is a critical step in linking the coupled physical–biogeochemical models to population dynamics of large pelagic predators. Here, we provide an example of a modeling approach with definitions
Senina, Inna, Lehodey, Patrick, Murtugudde, Raghu   +2 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Formal Modeling and Analysis of Organizations

, 2006
A new, formal, role-based, framework for modeling and analyzing both real world and artificial organizations is introduced. It exploits static and dynamic properties of the organizational model and includes the (frequently ignored) environment. The transition is described from a generic framework of an organization to its deployed model and to the ...
Broek, E.L. van den, Jonker, C.M., Sharpanskykh, A., Treur, J., Yolum, P.   +4 more
openaire   +5 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Workhorses of Biology research : model organisms

, 2020
In two centuries of modern scientific history, model organisms have contributed to our understanding of human physiology, cell biology, and diseases. But what are model organisms? What discoveries have they contributed to?
Trivedi, Deepti
core  

Yeast and filamentous fungi as model organisms in microbody research [PDF]

, 2006
Yeast and filamentous fungi are important model organisms in microbody research. The value of these organisms as models for higher eukaryotes is underscored by the observation that the principles of various aspects of microbody biology are strongly ...
Klei, Ida J. van der; id_orcid, Veenhuis, Marten,, Klei, Ida J. van der,, Veenhuis, Marten, van der Klei, Ida J., Klei, Ida J. van der   +5 more
core   +1 more source

1054 Serum cytokine kinetics in C57BL/6 versus BALB/c mice upon Con A and LPS stimulation in vivo

Journal for ImmunoTherapy of Cancer, 2023
Yi Li, Dongxiao Feng, Jian Fei, Ruilin Sun, Liping Feng, Xianfei X He   +5 more
doaj   +1 more source

Pro-regenerative potential of Artemisia annua L. essential oil: Toward a plant-derived ingredient for wound healing applications

Industrial Crops and Products
Artemisia annua L. is extensively cultivated for artemisinin, generating large amounts of aerial biomass, while its essential oil (AAO) remains underutilized.
Lixia Zhu, Xiang Meng, Xuting Song, Jiaxin Dong, Xianghe Meng, Kobil A. Bobokalonov, Hilola Ahunova, Komiljon Tojibaev, Meiying Jin, Min He, Mengmeng Sun   +10 more
doaj   +1 more source