Results 91 to 100 of about 2,691,356 (263)

Computationally Efficient Reduced Order Modeling of DFIG-Based Wind Turbines: A Novel Frequency-Weighted and Limited Model Reduction Approach With Error Bounds

open access: yesIEEE Access
In wind turbine engineering, stability and control rely on precision. A new approach for discrete-time systems is presented in this study, which makes use of constrained Gramians and frequency weights.
Muhammad Latif   +4 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Model Reduction for Discrete-Time Systems via Optimization over Grassmann Manifold

open access: yesMathematics
In this paper, we investigate h2-optimal model reduction methods for discrete-time linear time-invariant systems. Similar to the continuous-time case, we will formulate this problem as an optimization problem over a Grassmann manifold.
Yiqin Lin, Liping Zhou
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Data-driven nonlinear model reduction to spectral submanifolds in mechanical systems. [PDF]

open access: yesPhilos Trans A Math Phys Eng Sci, 2022
Cenedese M   +4 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

L2 Model Reduction and Variance Reduction

open access: yes, 1999
In this contribution we demonstrate that estimating a low order model (leaving some dynamics unmodeled) by L2 model reduction of a higher order estimated model may give smaller variance and mean square error than directly estimating it from the same data that produced the high order model.
Tjärnström, Fredrik, Ljung, Lennart
openaire   +2 more sources

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