Results 101 to 110 of about 19,179,679 (309)
An adaptive model reduction algorithm is proposed for systems of ODEs from chemical kinetics. Its goal is to provide an accurate approximation to the solution of these systems faster than could be obtained through straightforward numerical integration.
Adaptive Model Reduction
core
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
On Model Reductions of Boolean Networks
Boolean networks are a class of qualitative models used ex-tensively to model regulatory interactions driving biological processes.While structurally simple, their dynamics can be quite complex. One re-current issue in studying the dynamics of these models is state explosion.To tackle this problem model reduction techniques are employed ...
Claudine Chaouiya +2 more
openaire +3 more sources
Balanced truncation model reduction of periodic systems [PDF]
The balanced truncation approach to model reduction is considered for linear discrete-time periodic systems with time-varying dimensions. Stability of the reduced model is proved and a guaranteed additive bound is derived for the approximation error ...
Varga, Andras
core
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Model Reduction of LPV Control with Bounded Parameter Variation Rates [PDF]
This paper proposes a reduced-order controller of linear parameter varying systems. The parameters are available for measurement while their ranges and rates of variation are assumed to be bounded.
Riyanto, T. Bambang, Widowati, Widowati
core +1 more source
Reduction of Markov Chains Using a Value-of-Information-Based Approach
In this paper, we propose an approach to obtain reduced-order models of Markov chains. Our approach is composed of two information-theoretic processes. The first is a means of comparing pairs of stationary chains on different state spaces, which is done ...
Isaac J. Sledge, José C. Príncipe
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Ion channel model reduction using manifold boundaries [PDF]
Whittaker DG +6 more
europepmc +2 more sources
Entropy-Related Extremum Principles for Model Reduction of Dissipative Dynamical Systems
Chemical kinetic systems are modeled by dissipative ordinary differential equations involving multiple time scales. These lead to a phase flow generating anisotropic volume contraction.
Dirk Lebiedz
doaj +1 more source

