Results 111 to 120 of about 32,991,499 (363)

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Using the Prediction Model Risk of Bias Assessment Tool (PROBAST) to Evaluate Melanoma Prediction Studies. [PDF]

Cancers (Basel), 2022
Kaiser I, Mathes S, Pfahlberg AB, Uter W, Berking C, Heppt MV, Steeb T, Diehl K, Gefeller O.   +8 more
europepmc   +1 more source

Model Risk and Regulatory Capital [PDF]

capital requirements;(coherent) risk management;option pricing models;derivative pricing ...
Kerkhof, F.L.J., Melenberg, B., Schumacher, J.M.   +2 more
core   +1 more source

Risk measure modelling [PDF]

Interdisciplinary Management Research, 2007
As a phenomenon, risk represents a latent quantity of money or equivalent values needed as a guarantee. We would like to model in some essential way the approach to potential loss caused by various agents. If the interest focuses on security, it is necessary to determine a limit.
openaire   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Practice-relevant model validation: distributional parameter risk analysis in financial model risk management. [PDF]

Ann Oper Res, 2022
Cummins M, Gogolin F, Kearney F, Kiely G, Murphy B.   +4 more
europepmc   +1 more source

A Merton Model of Credit Risk with Jumps [PDF]

, 2015
In this note, we consider a Merton model for default risk, where the firm’s value is driven by a Brownian motion and a compound Poisson ...
Thao, Hoang Thi Phuong, Vuong, Quan-Hoang   +1 more
core  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Quantification of model risk that is caused by model misspecification. [PDF]

J Appl Stat, 2022
Seitshiro MB, Mashele HP.
europepmc   +1 more source

A Martian Quarantine Risk Model [PDF]

Structured model using loss functions to assess risk of using given decontamination procedure on all Martian unmanned landing ...
Cornell, R. G., Steg, S. E.
core   +1 more source